Are chimeric antigen receptor T cells (CAR-T cells) the long run in immunotherapy for autoimmune illnesses?
Goal: CAR-T cell remedy has revolutionized the remedy of oncological illnesses, and potential makes use of in autoimmune illnesses have just lately been described. The overview goals to combine the accessible knowledge on remedy with CAR-T cells, emphasizing autoimmune illnesses, to find out therapeutic advances and their doable future medical applicability in autoimmunity.
Supplies and strategies: A search was carried out in PubMed with the key phrases “Chimeric Antigen Receptor” and “CART cell”. The paperwork of curiosity have been chosen, and a essential overview of the data was carried out.
Outcomes: Within the remedy of autoimmune illnesses, in preclinical fashions, three completely different mobile methods have been used, which embody Chimeric antigen receptor T cells, Chimeric autoantibody receptor T cells, and Chimeric antigen receptor in regulatory T lymphocytes. All three sorts of remedy have been efficient. The potential antagonistic results inside them, cytokine launch syndrome, mobile toxicity and neurotoxicity should all the time be stored in thoughts.
Conclusions: Though info in people just isn’t but accessible, preclinical fashions of CAR-T cells within the remedy of autoimmune illnesses present promising outcomes, in order that sooner or later, they could turn out to be a helpful and efficient remedy within the remedy of those pathologies.
Ovalbumin Antigen-Particular Activation of Human T Cell Receptor Carefully Resembles Soluble Antibody Stimulation as Revealed by BOOST Phosphotyrosine Proteomics
Activation of the T cell receptor (TCR) results in a community of early signaling predominantly orchestrated by tyrosine phosphorylation in T cells. The TCR is usually activated utilizing soluble anti-TCR antibodies, however this method just isn’t antigen-specific. Alternatively, activating the TCR utilizing particular antigens of a spread of binding affinities within the type of a peptide-major histocompatibility advanced (pMHC) is presumed to be extra physiological. Nonetheless, because of the lack of wide-scale phosphotyrosine (pTyr) proteomic research straight evaluating anti-TCR antibodies and pMHC, a complete definition of those activated states stays enigmatic.
Elucidation of the tyrosine phosphoproteome utilizing quantitative pTyr proteomics permits a greater understanding of the distinctive options of those activating brokers and the position of ligand binding affinity on signaling. Right here, we apply the just lately established Broad-spectrum Optimization Of Selective Triggering (BOOST) to look at perturbations in tyrosine phosphorylation of human TCR triggered by anti-TCR antibodies and pMHC. Our knowledge reveal that high-affinity ovalbumin (OVA) pMHC activation of the human TCR triggers a largely related, albeit doubtlessly stronger, pTyr-mediated signaling regulatory axis in comparison with the anti-TCR antibody. The signaling output ensuing from OVA pMHC variants correlates properly with their weaker affinities, enabling affinity-tunable management of signaling energy. Collectively, we offer a framework for making use of BOOST to match pTyr-mediated signaling pathways of human T cells activated in an antigen-independent and antigen-specific method.
Bilateral anterior cerebral artery occlusion following CD19- and BCMA-targeted chimeric antigen receptor T-cell remedy for a myeloma affected person
Chimeric antigen receptor T (CAR-T)-cell remedy is a promising remedy for relapsed/refractory a number of myeloma (RRMM). In our earlier report, CD19- and BCMA-targeted CAR-T co-administration was related to a excessive response fee. Though cytokine launch syndrome (CRS) and neurotoxicity are frequent issues following CAR-T remedy, cerebral infarction is never reported as a CAR-T-related complication. We reported a 73-year-old feminine MM affected person who obtained CD19- and BCMA-targeted CAR-T for refractory illness.
Her illness responded to CAR-T remedy, however she developed neurological signs following CRS. Cranial CT and MRI demonstrated a number of cerebral infarctions and bilateral anterior cerebral artery (ACA) occlusion. We propose that cerebral infarction aside from CAR-T-related neurotoxicity is the underlying reason behind irregular neuropsychological signs, and diagnostic imaging assessments must be actively carried out to exclude ischemic cerebrovascular occasions.
CMV Control lentiviral particles (Neo) |
|||
| CMV-Null-Neo | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Neomycin marker under RSV promoter. |
|||
CMV Control lentiviral particles (Puro) |
|||
| CMV-Null-Puro | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Puromycin marker under RSV promoter. |
|||
EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV) |
|||
| LV694975 | ABM | 1.0 ug DNA | EUR 616.8 |
CMV Control lentiviral particles (GFP-Bsd) |
|||
| CMV-Null-GB | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Blasticidin fusion marker under RSV promoter. |
|||
CMV Control lentiviral particles (GFP-Puro) |
|||
| CMV-Null-GP | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Puromycin fusion marker under RSV promoter. |
|||
CMV Control lentiviral particles (RFP-Bsd) |
|||
| CMV-Null-RB | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Blasticidin fusion marker under RSV promoter. |
|||
CMV Control lentiviral particles (RFP-Puro) |
|||
| CMV-Null-RP | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Puromycin fusion marker under RSV promoter. |
|||
CMV control lentivirus (Hygro) |
|||
| CMV-Null-Hygro | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It has the hygromycin selection under RSV promoter. |
|||
CMV control lentivirus (Zeo) |
|||
| CMV-Null-Zeo | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It has the Zeocin selection under RSV promoter. |
|||
EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA) |
|||
| LV709564 | ABM | 1.0 ug DNA | EUR 379.2 |
EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro) |
|||
| LV709565 | ABM | 1.0 ug DNA | EUR 448.8 |
EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro) |
|||
| LV709566 | ABM | 1.0 ug DNA | EUR 448.8 |
EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA) |
|||
| LV694976 | ABM | 1.0 ug DNA | EUR 616.8 |
EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro) |
|||
| LV694977 | ABM | 1.0 ug DNA | EUR 686.4 |
EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro) |
|||
| LV694978 | ABM | 1.0 ug DNA | EUR 686.4 |
CMV Control lentiviral particles (Bsd) in PBS |
|||
| CMV-Null-Bsd-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the blasticidin marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
|||
CMV Control lentiviral particles (Neo) in PBS |
|||
| CMV-Null-Neo-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Neomycin marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
|||
CMV Control lentiviral particles (Puro) in PBS |
|||
| CMV-Null-Puro-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Puromycin marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
|||
CMV Control lentiviral particles (GFP-Bsd) in PBS |
|||
| CMV-Null-GB-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Blasticidin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
|||
CMV Control lentiviral particles (GFP-Puro) in PBS |
|||
| CMV-Null-GP-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Puromycin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
|||
CMV Control lentiviral particles (RFP-Bsd) in PBS |
|||
| CMV-Null-RB-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Blasticidin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
|||
CMV Control lentiviral particles (RFP-Puro) in PBS |
|||
| CMV-Null-RP-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
|
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Puromycin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
|||
EBAG9 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC) |
|||
| LV709567 | ABM | 1.0 ug DNA | EUR 379.2 |
EBAG9 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a) |
|||
| LV709568 | ABM | 1.0 ug DNA | EUR 379.2 |
MT1P3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701007 | ABM | 1.0 ug DNA | EUR 540 |
LOC284297 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701013 | ABM | 1.0 ug DNA | EUR 540 |
LOC149837 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701019 | ABM | 1.0 ug DNA | EUR 540 |
GHRLOS2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701025 | ABM | 1.0 ug DNA | EUR 540 |
LINC00469 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701031 | ABM | 1.0 ug DNA | EUR 540 |
INGX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701037 | ABM | 1.0 ug DNA | EUR 540 |
ABCA11P Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701049 | ABM | 1.0 ug DNA | EUR 540 |
NCOR1P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701061 | ABM | 1.0 ug DNA | EUR 540 |
ZDHHC8P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701067 | ABM | 1.0 ug DNA | EUR 540 |
FLJ26850 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701073 | ABM | 1.0 ug DNA | EUR 540 |
OCLM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701079 | ABM | 1.0 ug DNA | EUR 540 |
LINC00314 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701085 | ABM | 1.0 ug DNA | EUR 540 |
GSTTP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701091 | ABM | 1.0 ug DNA | EUR 540 |
LOC285679 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701097 | ABM | 1.0 ug DNA | EUR 540 |
VN1R3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701103 | ABM | 1.0 ug DNA | EUR 540 |
MT1DP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701115 | ABM | 1.0 ug DNA | EUR 540 |
LINC00313 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701127 | ABM | 1.0 ug DNA | EUR 540 |
LOC222699 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701139 | ABM | 1.0 ug DNA | EUR 540 |
LINC00161 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701145 | ABM | 1.0 ug DNA | EUR 540 |
LOC440419 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701151 | ABM | 1.0 ug DNA | EUR 540 |
KCNQ1DN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701157 | ABM | 1.0 ug DNA | EUR 540 |
RBMS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701175 | ABM | 1.0 ug DNA | EUR 540 |
MIR22HG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701181 | ABM | 1.0 ug DNA | Ask for price |
C22orf34 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701187 | ABM | 1.0 ug DNA | EUR 540 |
ZNF663 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701193 | ABM | 1.0 ug DNA | EUR 540 |
AKR1CL1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701199 | ABM | 1.0 ug DNA | EUR 540 |
HMGB3P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701205 | ABM | 1.0 ug DNA | EUR 540 |
ASIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701211 | ABM | 1.0 ug DNA | EUR 540 |
LOC149950 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701217 | ABM | 1.0 ug DNA | EUR 540 |
BOLA2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701223 | ABM | 1.0 ug DNA | EUR 540 |
LOC441108 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701229 | ABM | 1.0 ug DNA | EUR 540 |
FLJ16126 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701235 | ABM | 1.0 ug DNA | EUR 540 |
LOC728032 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701241 | ABM | 1.0 ug DNA | EUR 540 |
C21orf67 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701253 | ABM | 1.0 ug DNA | EUR 540 |
TP53TG3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701259 | ABM | 1.0 ug DNA | EUR 540 |
OSTBETA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701265 | ABM | 1.0 ug DNA | EUR 540 |
FLJ33360 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701271 | ABM | 1.0 ug DNA | EUR 540 |
LOC441208 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701277 | ABM | 1.0 ug DNA | EUR 540 |
C12orf36 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701283 | ABM | 1.0 ug DNA | EUR 540 |
LOC153684 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701289 | ABM | 1.0 ug DNA | EUR 540 |
LOC399900 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701295 | ABM | 1.0 ug DNA | EUR 540 |
LOC149134 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701301 | ABM | 1.0 ug DNA | EUR 540 |
LINC00173 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701313 | ABM | 1.0 ug DNA | EUR 540 |
LITAF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701319 | ABM | 1.0 ug DNA | EUR 540 |
HIST1H2AI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701325 | ABM | 1.0 ug DNA | EUR 540 |
LOC440905 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701331 | ABM | 1.0 ug DNA | EUR 540 |
LOC339535 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701337 | ABM | 1.0 ug DNA | EUR 540 |
LOC643210 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701343 | ABM | 1.0 ug DNA | EUR 540 |
LOC440337 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701349 | ABM | 1.0 ug DNA | EUR 540 |
BEX1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701355 | ABM | 1.0 ug DNA | EUR 540 |
HIST2H2AA4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701361 | ABM | 1.0 ug DNA | EUR 540 |
LPAL2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701367 | ABM | 1.0 ug DNA | EUR 540 |
LOC340094 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701373 | ABM | 1.0 ug DNA | EUR 540 |
LINC00574 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701379 | ABM | 1.0 ug DNA | EUR 540 |
CIB2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701385 | ABM | 1.0 ug DNA | EUR 540 |
SNX12 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701397 | ABM | 1.0 ug DNA | EUR 540 |
FLJ44006 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701403 | ABM | 1.0 ug DNA | EUR 540 |
C15orf37 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701409 | ABM | 1.0 ug DNA | EUR 540 |
PLAC2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701415 | ABM | 1.0 ug DNA | EUR 540 |
BTG2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701421 | ABM | 1.0 ug DNA | EUR 540 |
FLJ40448 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701445 | ABM | 1.0 ug DNA | EUR 540 |
CIB3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701451 | ABM | 1.0 ug DNA | EUR 540 |
PRDX5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701457 | ABM | 1.0 ug DNA | EUR 540 |
FLJ45256 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701463 | ABM | 1.0 ug DNA | EUR 540 |
C21orf67 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701469 | ABM | 1.0 ug DNA | EUR 540 |
LINC00477 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701475 | ABM | 1.0 ug DNA | EUR 540 |
LOC348262 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701487 | ABM | 1.0 ug DNA | EUR 540 |
SHISA4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701493 | ABM | 1.0 ug DNA | EUR 540 |
LOC400707 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701499 | ABM | 1.0 ug DNA | EUR 540 |
FLJ41423 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701505 | ABM | 1.0 ug DNA | EUR 540 |
FLJ46257 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701511 | ABM | 1.0 ug DNA | EUR 540 |
FKSG83 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701517 | ABM | 1.0 ug DNA | EUR 540 |
FLJ25328 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701523 | ABM | 1.0 ug DNA | EUR 540 |
LOC84931 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701529 | ABM | 1.0 ug DNA | EUR 540 |
LOC389791 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701535 | ABM | 1.0 ug DNA | EUR 540 |
LOC338809 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701541 | ABM | 1.0 ug DNA | EUR 540 |
LOC441251 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701553 | ABM | 1.0 ug DNA | EUR 540 |
INSL6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701559 | ABM | 1.0 ug DNA | EUR 540 |
C1orf222 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701565 | ABM | 1.0 ug DNA | EUR 540 |
SFTPA2B Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701571 | ABM | 1.0 ug DNA | EUR 540 |
CCDC102B Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701595 | ABM | 1.0 ug DNA | EUR 540 |
C1QTNF3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701601 | ABM | 1.0 ug DNA | EUR 540 |
OTOGL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701607 | ABM | 1.0 ug DNA | EUR 540 |
LHPP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701613 | ABM | 1.0 ug DNA | EUR 540 |
TICAM2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701619 | ABM | 1.0 ug DNA | EUR 540 |
CHMP4A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701625 | ABM | 1.0 ug DNA | EUR 540 |
ALKBH3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701631 | ABM | 1.0 ug DNA | EUR 540 |
FBP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701637 | ABM | 1.0 ug DNA | EUR 540 |
CLEC12A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701643 | ABM | 1.0 ug DNA | EUR 540 |
OR2C1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701649 | ABM | 1.0 ug DNA | EUR 540 |
TMEM182 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701655 | ABM | 1.0 ug DNA | EUR 540 |
LOC339524 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701661 | ABM | 1.0 ug DNA | EUR 540 |
SEPSECS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701667 | ABM | 1.0 ug DNA | EUR 540 |
Selv Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701673 | ABM | 1.0 ug DNA | EUR 540 |
GPR87 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701679 | ABM | 1.0 ug DNA | EUR 540 |
ASTN2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701685 | ABM | 1.0 ug DNA | EUR 540 |
MAGEB3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701691 | ABM | 1.0 ug DNA | EUR 540 |
SSTr4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701709 | ABM | 1.0 ug DNA | EUR 540 |
ACOT4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701715 | ABM | 1.0 ug DNA | EUR 540 |
ZNF672 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701721 | ABM | 1.0 ug DNA | EUR 540 |
SLC16A3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701727 | ABM | 1.0 ug DNA | EUR 540 |
CTBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701739 | ABM | 1.0 ug DNA | EUR 540 |
APOL1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701745 | ABM | 1.0 ug DNA | EUR 540 |
ST8SIA1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701751 | ABM | 1.0 ug DNA | EUR 540 |
MTERF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701757 | ABM | 1.0 ug DNA | EUR 540 |
ALG13 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701763 | ABM | 1.0 ug DNA | EUR 540 |
ATF2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701769 | ABM | 1.0 ug DNA | EUR 540 |
AHCYL1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701775 | ABM | 1.0 ug DNA | EUR 540 |
ZKSCAN1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701781 | ABM | 1.0 ug DNA | EUR 540 |
PTH1R Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701787 | ABM | 1.0 ug DNA | EUR 540 |
LOC553158 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701793 | ABM | 1.0 ug DNA | EUR 540 |
PIK3R2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701799 | ABM | 1.0 ug DNA | EUR 540 |
EBF3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701805 | ABM | 1.0 ug DNA | EUR 540 |
R3HDM2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701811 | ABM | 1.0 ug DNA | EUR 540 |
KCNN2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701817 | ABM | 1.0 ug DNA | EUR 540 |
SPIRE1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701823 | ABM | 1.0 ug DNA | EUR 540 |
TTC26 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701835 | ABM | 1.0 ug DNA | EUR 540 |
ARSJ Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701841 | ABM | 1.0 ug DNA | EUR 540 |
SNX18 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701847 | ABM | 1.0 ug DNA | EUR 540 |
PYHIN1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701853 | ABM | 1.0 ug DNA | EUR 540 |
ZNF587 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701859 | ABM | 1.0 ug DNA | EUR 540 |
CDADC1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701865 | ABM | 1.0 ug DNA | EUR 540 |
FIP1L1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701871 | ABM | 1.0 ug DNA | EUR 540 |
GALNT3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701877 | ABM | 1.0 ug DNA | EUR 540 |
P4HA3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701889 | ABM | 1.0 ug DNA | EUR 540 |
IFFO1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701895 | ABM | 1.0 ug DNA | EUR 540 |
GRAMD4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701901 | ABM | 1.0 ug DNA | EUR 540 |
ZNF254 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701907 | ABM | 1.0 ug DNA | EUR 540 |
IREB2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701919 | ABM | 1.0 ug DNA | EUR 540 |
RBM26 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701925 | ABM | 1.0 ug DNA | EUR 540 |
ZBTB24 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701931 | ABM | 1.0 ug DNA | EUR 540 |
NLGN4Y Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701937 | ABM | 1.0 ug DNA | EUR 540 |
HSPA4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701943 | ABM | 1.0 ug DNA | EUR 540 |
GRM2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701949 | ABM | 1.0 ug DNA | EUR 540 |
EphA7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701955 | ABM | 1.0 ug DNA | EUR 540 |
TUT1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701967 | ABM | 1.0 ug DNA | EUR 540 |
PKD2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701973 | ABM | 1.0 ug DNA | EUR 540 |
HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701979 | ABM | 1.0 ug DNA | EUR 540 |
MCTP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701985 | ABM | 1.0 ug DNA | EUR 540 |
STON2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701991 | ABM | 1.0 ug DNA | EUR 540 |
C17orf70 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV701997 | ABM | 1.0 ug DNA | EUR 540 |
The Intracellular Area of CD40 is a Potent Costimulatory Component in Chimeric Antigen Receptors
The costimulatory domains included into second-generation and third-generation chimeric antigen receptors (CARs) strongly affect CAR-T-cell operate. Right here, we explored second-generation and third-generation CARs harboring the signaling area of the CD40 receptor as a brand new costimulatory aspect as compared with related CARs carrying the 4-1BB area. In CARs of each generations, CD40 was stronger than 4-1BB in triggering the NF-κB signaling pathway.
In human T cells from 2 donors, CD40 was akin to 4-1BB in upregulating costimulatory and activation markers, inducing proinflammatory cytokine secretion and mediating goal cell killing. Apparently, variations within the response sample of T cells from the two donors with respect to CD40 and 4-1BB have been evident. We conclude that in human T cells, the CD40 signaling area is a potent costimulatory aspect in each second-generation and third-generation CARs.
A Systematic Overview of the Function of Chimeric Antigen Receptor T (CAR-T) Cell Remedy within the Therapy of Strong Tumors
Chimeric antigen receptor T (CAR-T) cell remedy makes use of sufferers’ personal T lymphocytes which might be engineered to assault most cancers cells. It’s Meals and Drug Administration (FDA)-approved in numerous hematological malignancies and presently being evaluated in strong cancers in early section research. We did a scientific overview consisting of 15 potential medical trials (n=159) evaluating CAR-T cells in strong cancers. Early section trials confirmed promising response charges in ovarian epithelial most cancers (100%), human epidermal progress issue receptor 2 (HER2)-positive sarcoma (67%), epidermal progress issue receptor (EGFR)-positive biliary tract most cancers (65%), superior gastric/pancreatic most cancers (82%), hepatocellular carcinoma (67%), and colorectal most cancers (70%).
The median general response throughout all malignancies was 62% (vary 17%-100%). Median progression-free survival and general survival weren’t reached in most trials. Cytokine launch syndrome was seen in just one affected person with cholangiocarcinoma who obtained EGFR-specific CAR-T cell remedy. Though survival knowledge continues to be not mature, CAR-T cell remedy in strong malignancies did present encouraging response charges and was well-tolerated.
Variations in lymphoma sufferers between chimeric antigen receptor T-cell remedy trials and the overall inhabitants
Chimeric antigen receptor (CAR)-T cell therapies seem to be promising therapies for non-Hodgkin’s and B-cell lymphoma. Nonetheless, a number of CAR-T therapies accredited by the US Meals and Drug Administration have solely been examined for efficacy in comparatively few single-arm medical trials with small pattern sizes. We sought to look at the variations between sufferers in these trials and the overall inhabitants of sufferers with non-Hodgkin’s and B-cell lymphoma. 5 hundred and twenty-two sufferers from 15 CAR-T trials present in a scientific overview and 417,492 sufferers from the Surveillance, Epidemiology, and Finish Outcomes (SEER) Program database have been in contrast.
CAR-T research individuals seemed to be youthful (46.7% beneath 70 years previous vs. 42.2%), extra male (68.0% vs. 55.7%), and adopted for a shorter time period in comparison with sufferers within the SEER inhabitants (imply [M] 45.6 months, 95% confidence interval [CI] 17.7 to 63.three months follow-up vs. M 57.1 months, 95% CI 57.Zero to 57.three months survival). CAR-T research individuals might differ considerably from the overall inhabitants of sufferers with non-Hodgkin’s and B-cell lymphoma. Effectiveness of CAR-T therapies within the common inhabitants of lymphoma sufferers might differ from effectiveness demonstrated in trials. Newly created CAR-T affected person registries are important to establishing population-level effectiveness of the therapies.
Recombinant Human ITGB1 Protein, His, E.coli-2ug |
|||
| QP12462-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ITGB1 Protein, His, E.coli-5ug |
|||
| QP12462-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human ITGB1 Protein, His, E.coli-1mg |
|||
| QP12462-HIS-EC-1mg | EnQuireBio | 1mg | EUR 3308.4 |
ITGB1 protein (His tag) |
|||
| 80R-3617 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Purified recombinant ITGB1 protein (His tag) |
|||
Human Integrin Beta 1 (ITGb1) ELISA Kit |
|||
| DLR-ITGb1-Hu-48T | DL Develop | 48T | EUR 597.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Beta 1 (ITGb1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
Human Integrin Beta 1 (ITGb1) ELISA Kit |
|||
| DLR-ITGb1-Hu-96T | DL Develop | 96T | EUR 776.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Beta 1 (ITGb1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
Human Integrin Beta 1 (ITGb1) ELISA Kit |
|||
| RD-ITGb1-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 600 |
Human Integrin Beta 1 (ITGb1) ELISA Kit |
|||
| RD-ITGb1-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 830.4 |
Human Integrin Beta 1 (ITGb1) ELISA Kit |
|||
| RDR-ITGb1-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 626.4 |
Human Integrin Beta 1 (ITGb1) ELISA Kit |
|||
| RDR-ITGb1-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 868.8 |
Recombinant Human ITGB1 Protein, His, Insect-1mg |
|||
| QP12462-HIS-INSECT-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant (E.coli) Human CD40 (aa: 21-193, His Tag, >95% Pure) |
|||
| HCD4015-N-10 | Alpha Diagnostics | 10 ug | EUR 343.2 |
XMIR-21 RNA oligo miRNA-21-5p with Xmotif |
|||
| XMIR-21 | SBI | 10 rxn | EUR 525.6 |
AXMIR-21 RNA oligo anti-miRNA-21-5p with Xmotif |
|||
| AXMIR-21 | SBI | 10 reactions | EUR 525.6 |
Recombinant (E.Coli, His-tag) Human Syndecan-4, His-tag |
|||
| RP-993 | Alpha Diagnostics | 10 ug | EUR 270 |
ICP Quality Control Standard 21 |
|||
| QC-21 | Scientific Laboratory Supplies | 125ML | EUR 337.44 |
Recombinant (E.coli) Rat CD40 (aa: 21-193, His Tag, >95% Pure) |
|||
| RCD4015-N-10 | Alpha Diagnostics | 10 ug | EUR 255.6 |
FGF-21 Fibroblast Growth Factor-21 Human Recombinant Protein, His Tag |
|||
| PROTQ9NSA1 | BosterBio | Regular: 50ug | EUR 380.4 |
|
Description: Fibroblast Growth Factor -21 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 202 amino acids (29-209) and having a molecular mass of 21.6 kDa (molecular weight on SDS-PAGE will appear higher). ;The FGF-21 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. |
|||
Recombinant (E.Coli, His-tag) Human HTRA2 |
|||
| RP-413 | Alpha Diagnostics | 10 ug | EUR 270 |
Recombinant (E.Coli, His-tag) Human STAT1 |
|||
| RP-722 | Alpha Diagnostics | 10 ug | EUR 343.2 |
Recombinant (E.Coli, His-tag) Human S100b |
|||
| RP-774 | Alpha Diagnostics | 10 ug | EUR 343.2 |
Recombinant (E.Coli, His-tag) Human Osteocrin |
|||
| RP-868 | Alpha Diagnostics | 10 ug | EUR 343.2 |
Recombinant (E.Coli, His-tag) Human CD29 |
|||
| RP-915 | Alpha Diagnostics | 2 ug | EUR 416.4 |
Recombinant (E.Coli, His-tag) Human Geminin |
|||
| RP-989 | Alpha Diagnostics | 5 ug | EUR 196.8 |
Recombinant Human Fibroblast Growth Factor-21, His Tag |
|||
| 7-00385 | CHI Scientific | 10µg | Ask for price |
Recombinant Human Fibroblast Growth Factor-21, His Tag |
|||
| 7-00386 | CHI Scientific | 50µg | Ask for price |
Recombinant Human Fibroblast Growth Factor-21, His Tag |
|||
| 7-00387 | CHI Scientific | 1mg | Ask for price |
XMIRXpress lentivector miRNA-21-5p with Xmotif |
|||
| XMIRXP-21 | SBI | 10 ug | EUR 812.4 |
Recombinant E.coli LACTB Protein, His, E.coli-20ug |
|||
| QP12522-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant E.coli LACTB Protein, His, E.coli-5ug |
|||
| QP12522-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant (E.Coli, His-tag) Human Ubiquitin Conjugating enzyme 7, His-tag |
|||
| RP-425 | Alpha Diagnostics | 10 ug | EUR 270 |
Histidine-tag (poly-His/Hisx6) Protein (His-tag-fusion protein) ELISA Kit, 96 tests, Quantitative |
|||
| 800-440-HIS | Alpha Diagnostics | 1 kit | EUR 1074 |
Recombinant Human ACPP Protein, His, E.coli-100ug |
|||
| QP10946-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human ACPP Protein, His, E.coli-10ug |
|||
| QP10946-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ACPP Protein, His, E.coli-1mg |
|||
| QP10946-HIS-1mg | EnQuireBio | 1mg | EUR 4386 |
Recombinant Human ACPP Protein, His, E.coli-20ug |
|||
| QP10946-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human ACPP Protein, His, E.coli-2ug |
|||
| QP10946-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ACPP Protein, His, E.coli-5ug |
|||
| QP10946-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human ADAM10 Protein, His, E.coli-10ug |
|||
| QP10961-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ADAM10 Protein, His, E.coli-1mg |
|||
| QP10961-HIS-1mg | EnQuireBio | 1mg | EUR 5821.2 |
Recombinant Human ADAM10 Protein, His, E.coli-1ug |
|||
| QP10961-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human ADAM10 Protein, His, E.coli-2ug |
|||
| QP10961-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ADAM10 Protein, His, E.coli-50ug |
|||
| QP10961-HIS-50ug | EnQuireBio | 50ug | EUR 1513.2 |
Recombinant Human ADAM10 Protein, His, E.coli-5ug |
|||
| QP10961-HIS-5ug | EnQuireBio | 5ug | EUR 241.2 |
Recombinant Human ADH1A Protein, His, E.coli-10ug |
|||
| QP10966-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ADH1A Protein, His, E.coli-20ug |
|||
| QP10966-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human ADH1A Protein, His, E.coli-2ug |
|||
| QP10966-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ADH1A Protein, His, E.coli-5ug |
|||
| QP10966-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human Adipsin Protein, His, E.coli-10ug |
|||
| QP10969-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human Adipsin Protein, His, E.coli-20ug |
|||
| QP10969-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human Adipsin Protein, His, E.coli-2ug |
|||
| QP10969-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human Adipsin Protein, His, E.coli-5ug |
|||
| QP10969-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human AKR1D1 Protein, His, E.coli-20ug |
|||
| QP10995-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human AKR1D1 Protein, His, E.coli-5ug |
|||
| QP10995-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human AMBP Protein, His, E.coli-10ug |
|||
| QP11009-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human AMBP Protein, His, E.coli-1mg |
|||
| QP11009-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human AMBP Protein, His, E.coli-2ug |
|||
| QP11009-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ANGPTL3 Protein, His, E.coli-100ug |
|||
| QP11018-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human ANGPTL3 Protein, His, E.coli-1mg |
|||
| QP11018-HIS-1mg | EnQuireBio | 1mg | EUR 5821.2 |
Recombinant Human APOA5 Protein, His, E.coli-2ug |
|||
| QP11046-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ATP1B1 Protein, His, E.coli-10ug |
|||
| QP11104-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ATP1B1 Protein, His, E.coli-20ug |
|||
| QP11104-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human ATP1B1 Protein, His, E.coli-2ug |
|||
| QP11104-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ATP1B1 Protein, His, E.coli-5ug |
|||
| QP11104-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human ATP1B2 Protein, His, E.coli-10ug |
|||
| QP11105-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ATP1B2 Protein, His, E.coli-20ug |
|||
| QP11105-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human ATP1B2 Protein, His, E.coli-2ug |
|||
| QP11105-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ATP1B2 Protein, His, E.coli-5ug |
|||
| QP11105-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human AZGP1 Protein, His, E.coli-1mg |
|||
| QP11114-HIS-1mg | EnQuireBio | 1mg | EUR 4386 |
Recombinant Human AZGP1 Protein, His, E.coli-20ug |
|||
| QP11114-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human AZGP1 Protein, His, E.coli-5ug |
|||
| QP11114-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human B2M Protein, His, E.coli-1ug |
|||
| QP11117-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human B2M Protein, His, E.coli-50ug |
|||
| QP11117-HIS-50ug | EnQuireBio | 50ug | EUR 1393.2 |
Recombinant Human B2M Protein, His, E.coli-5ug |
|||
| QP11117-HIS-5ug | EnQuireBio | 5ug | EUR 241.2 |
Recombinant Human BIRC7 Protein, His, E.coli-20ug |
|||
| QP11164-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human BIRC7 Protein, His, E.coli-5ug |
|||
| QP11164-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human IGFBP7 Protein, His, E.coli-100ug |
|||
| QP12384-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human IGFBP7 Protein, His, E.coli-10ug |
|||
| QP12384-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human IGFBP7 Protein, His, E.coli-2ug |
|||
| QP12384-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human IL13RA2 Protein, His, E.coli-10ug |
|||
| QP12406-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human IL13RA2 Protein, His, E.coli-20ug |
|||
| QP12406-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human IL13RA2 Protein, His, E.coli-2ug |
|||
| QP12406-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human IL13RA2 Protein, His, E.coli-5ug |
|||
| QP12406-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human KLF4 Protein, His, E.coli-20ug |
|||
| QP12498-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLF4 Protein, His, E.coli-5ug |
|||
| QP12498-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human KLK15 Protein, His, E.coli-1mg |
|||
| QP12504-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human KLK15 Protein, His, E.coli-1ug |
|||
| QP12504-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human KLK15 Protein, His, E.coli-20ug |
|||
| QP12504-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLK15 Protein, His, E.coli-50ug |
|||
| QP12504-HIS-50ug | EnQuireBio | 50ug | EUR 1513.2 |
Recombinant Human KLK2 Protein, His, E.coli-1mg |
|||
| QP12505-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human KLK2 Protein, His, E.coli-1ug |
|||
| QP12505-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human KLK2 Protein, His, E.coli-20ug |
|||
| QP12505-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLK2 Protein, His, E.coli-50ug |
|||
| QP12505-HIS-50ug | EnQuireBio | 50ug | EUR 1393.2 |
Recombinant Human KLK3 Protein, His, E.coli-1mg |
|||
| QP12506-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human KLK3 Protein, His, E.coli-20ug |
|||
| QP12506-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLK3 Protein, His, E.coli-5ug |
|||
| QP12506-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human KLK5 Protein, His, E.coli-100ug |
|||
| QP12507-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human KLK5 Protein, His, E.coli-1mg |
|||
| QP12507-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human KLRB1 Protein, His, E.coli-1mg |
|||
| QP12508-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human KLRB1 Protein, His, E.coli-1ug |
|||
| QP12508-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human KLRB1 Protein, His, E.coli-20ug |
|||
| QP12508-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLRB1 Protein, His, E.coli-50ug |
|||
| QP12508-HIS-50ug | EnQuireBio | 50ug | EUR 1513.2 |
Recombinant Human LHRH Protein, His, E.coli-1mg |
|||
| QP12569-HIS-1mg | EnQuireBio | 1mg | EUR 4386 |
Recombinant Human LHRH Protein, His, E.coli-20ug |
|||
| QP12569-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human LHRH Protein, His, E.coli-5ug |
|||
| QP12569-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human LIN28 Protein, His, E.coli-10ug |
|||
| QP12571-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human LIN28 Protein, His, E.coli-2ug |
|||
| QP12571-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human LIPG Protein, His, E.coli-10ug |
|||
| QP12577-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human LIPG Protein, His, E.coli-20ug |
|||
| QP12577-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human LIPG Protein, His, E.coli-2ug |
|||
| QP12577-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human LIPG Protein, His, E.coli-5ug |
|||
| QP12577-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human LPL Protein, His, E.coli-10ug |
|||
| QP12581-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human LPL Protein, His, E.coli-1mg |
|||
| QP12581-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human LPL Protein, His, E.coli-2ug |
|||
| QP12581-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human LRG1 Protein, His, E.coli-1mg |
|||
| QP12583-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human LRG1 Protein, His, E.coli-20ug |
|||
| QP12583-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human LRG1 Protein, His, E.coli-5ug |
|||
| QP12583-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human LUM Protein, His, E.coli-10ug |
|||
| QP12598-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human LUM Protein, His, E.coli-20ug |
|||
| QP12598-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human LUM Protein, His, E.coli-2ug |
|||
| QP12598-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human LUM Protein, His, E.coli-5ug |
|||
| QP12598-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human LYVE1 Protein, His, E.coli-1mg |
|||
| QP12609-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human MAPK1 Protein, His, E.coli-1mg |
|||
| QP12639-HIS-1mg | EnQuireBio | 1mg | EUR 2774.4 |
Recombinant Human MAPK1 Protein, His, E.coli-25ug |
|||
| QP12639-HIS-25ug | EnQuireBio | 25ug | EUR 241.2 |
Recombinant Human MAPK1 Protein, His, E.coli-5ug |
|||
| QP12639-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human MFAP4 Protein, His, E.coli-10ug |
|||
| QP12691-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human MFAP4 Protein, His, E.coli-20ug |
|||
| QP12691-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human MFAP4 Protein, His, E.coli-2ug |
|||
| QP12691-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human MFAP4 Protein, His, E.coli-5ug |
|||
| QP12691-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human NARS Protein, His, E.coli-100ug |
|||
| QP12794-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human NARS Protein, His, E.coli-1mg |
|||
| QP12794-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human NXPH1 Protein, His, E.coli-10ug |
|||
| QP12912-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human NXPH1 Protein, His, E.coli-20ug |
|||
| QP12912-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human NXPH1 Protein, His, E.coli-2ug |
|||
| QP12912-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human NXPH1 Protein, His, E.coli-5ug |
|||
| QP12912-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human PDCD1LG2 Protein, His, E.coli-10ug |
|||
| QP12985-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human PDCD1LG2 Protein, His, E.coli-20ug |
|||
| QP12985-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PDCD1LG2 Protein, His, E.coli-2ug |
|||
| QP12985-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human PDCD1LG2 Protein, His, E.coli-5ug |
|||
| QP12985-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human PEDF Protein, His, E.coli-1mg |
|||
| QP13005-HIS-1mg | EnQuireBio | 1mg | EUR 3667.2 |
Recombinant Human PEDF Protein, His, E.coli-20ug |
|||
| QP13005-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PEDF Protein, His, E.coli-5ug |
|||
| QP13005-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human PSG1 Protein, His, E.coli-10ug |
|||
| QP13179-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human PSG1 Protein, His, E.coli-20ug |
|||
| QP13179-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PSG1 Protein, His, E.coli-2ug |
|||
| QP13179-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human PSG1 Protein, His, E.coli-5ug |
|||
| QP13179-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human PSG5 Protein, His, E.coli-1mg |
|||
| QP13180-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human PSG5 Protein, His, E.coli-1ug |
|||
| QP13180-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human PSG5 Protein, His, E.coli-20ug |
|||
| QP13180-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PSG5 Protein, His, E.coli-50ug |
|||
| QP13180-HIS-50ug | EnQuireBio | 50ug | EUR 1393.2 |
Recombinant Human PTEN Protein, His, E.coli-100ug |
|||
| QP13199-HIS-0.1mg | EnQuireBio | 100ug | EUR 1698 |
Recombinant Human PTEN Protein, His, E.coli-1ug |
|||
| QP13199-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human PTX3 Protein, His, E.coli-10ug |
|||
| QP13217-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human PTX3 Protein, His, E.coli-20ug |
|||
| QP13217-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PTX3 Protein, His, E.coli-2ug |
|||
| QP13217-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human PTX3 Protein, His, E.coli-5ug |
|||
| QP13217-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human RBP4 Protein, His, E.coli-10ug |
|||
| QP13283-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human RBP4 Protein, His, E.coli-2ug |
|||
| QP13283-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human REN Protein, His, E.coli-10ug |
|||
| QP13296-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human REN Protein, His, E.coli-25ug |
|||
| QP13296-HIS-25ug | EnQuireBio | 25ug | EUR 241.2 |
Recombinant Human REN Protein, His, E.coli-2ug |
|||
| QP13296-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human REN Protein, His, E.coli-5ug |
|||
| QP13296-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human RLBP1 Protein, His, E.coli-10ug |
|||
| QP13321-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human RLBP1 Protein, His, E.coli-20ug |
|||
| QP13321-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human RLBP1 Protein, His, E.coli-2ug |
|||
| QP13321-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human RLBP1 Protein, His, E.coli-5ug |
|||
| QP13321-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human RLN2 Protein, His, E.coli-1mg |
|||
| QP13322-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human RLN2 Protein, His, E.coli-1ug |
|||
| QP13322-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human RLN2 Protein, His, E.coli-25ug |
|||
| QP13322-HIS-25ug | EnQuireBio | 25ug | EUR 241.2 |
Recombinant Human RLN2 Protein, His, E.coli-50ug |
|||
| QP13322-HIS-50ug | EnQuireBio | 50ug | EUR 1273.2 |
Recombinant Human RNASE3 Protein, His, E.coli-10ug |
|||
| QP13323-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human RNASE3 Protein, His, E.coli-20ug |
|||
| QP13323-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human RNASE3 Protein, His, E.coli-2ug |
|||
| QP13323-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human RNASE3 Protein, His, E.coli-5ug |
|||
| QP13323-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human S100A8 Protein, His, E.coli-10ug |
|||
| QP13399-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |