Are chimeric antigen receptor T cells (CAR-T cells) the long run in immunotherapy for autoimmune illnesses?
Goal: CAR-T cell remedy has revolutionized the remedy of oncological illnesses, and potential makes use of in autoimmune illnesses have just lately been described. The overview goals to combine the accessible knowledge on remedy with CAR-T cells, emphasizing autoimmune illnesses, to find out therapeutic advances and their doable future medical applicability in autoimmunity.
Supplies and strategies: A search was carried out in PubMed with the key phrases “Chimeric Antigen Receptor” and “CART cell”. The paperwork of curiosity have been chosen, and a essential overview of the data was carried out.
Outcomes: Within the remedy of autoimmune illnesses, in preclinical fashions, three completely different mobile methods have been used, which embody Chimeric antigen receptor T cells, Chimeric autoantibody receptor T cells, and Chimeric antigen receptor in regulatory T lymphocytes. All three sorts of remedy have been efficient. The potential antagonistic results inside them, cytokine launch syndrome, mobile toxicity and neurotoxicity should all the time be stored in thoughts.
Conclusions: Though info in people just isn’t but accessible, preclinical fashions of CAR-T cells within the remedy of autoimmune illnesses present promising outcomes, in order that sooner or later, they could turn out to be a helpful and efficient remedy within the remedy of those pathologies.
Ovalbumin Antigen-Particular Activation of Human T Cell Receptor Carefully Resembles Soluble Antibody Stimulation as Revealed by BOOST Phosphotyrosine Proteomics
Activation of the T cell receptor (TCR) results in a community of early signaling predominantly orchestrated by tyrosine phosphorylation in T cells. The TCR is usually activated utilizing soluble anti-TCR antibodies, however this method just isn’t antigen-specific. Alternatively, activating the TCR utilizing particular antigens of a spread of binding affinities within the type of a peptide-major histocompatibility advanced (pMHC) is presumed to be extra physiological. Nonetheless, because of the lack of wide-scale phosphotyrosine (pTyr) proteomic research straight evaluating anti-TCR antibodies and pMHC, a complete definition of those activated states stays enigmatic.
Elucidation of the tyrosine phosphoproteome utilizing quantitative pTyr proteomics permits a greater understanding of the distinctive options of those activating brokers and the position of ligand binding affinity on signaling. Right here, we apply the just lately established Broad-spectrum Optimization Of Selective Triggering (BOOST) to look at perturbations in tyrosine phosphorylation of human TCR triggered by anti-TCR antibodies and pMHC. Our knowledge reveal that high-affinity ovalbumin (OVA) pMHC activation of the human TCR triggers a largely related, albeit doubtlessly stronger, pTyr-mediated signaling regulatory axis in comparison with the anti-TCR antibody. The signaling output ensuing from OVA pMHC variants correlates properly with their weaker affinities, enabling affinity-tunable management of signaling energy. Collectively, we offer a framework for making use of BOOST to match pTyr-mediated signaling pathways of human T cells activated in an antigen-independent and antigen-specific method.
Bilateral anterior cerebral artery occlusion following CD19- and BCMA-targeted chimeric antigen receptor T-cell remedy for a myeloma affected person
Chimeric antigen receptor T (CAR-T)-cell remedy is a promising remedy for relapsed/refractory a number of myeloma (RRMM). In our earlier report, CD19- and BCMA-targeted CAR-T co-administration was related to a excessive response fee. Though cytokine launch syndrome (CRS) and neurotoxicity are frequent issues following CAR-T remedy, cerebral infarction is never reported as a CAR-T-related complication. We reported a 73-year-old feminine MM affected person who obtained CD19- and BCMA-targeted CAR-T for refractory illness.
Her illness responded to CAR-T remedy, however she developed neurological signs following CRS. Cranial CT and MRI demonstrated a number of cerebral infarctions and bilateral anterior cerebral artery (ACA) occlusion. We propose that cerebral infarction aside from CAR-T-related neurotoxicity is the underlying reason behind irregular neuropsychological signs, and diagnostic imaging assessments must be actively carried out to exclude ischemic cerebrovascular occasions.
CMV Control lentiviral particles (Neo) |
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| CMV-Null-Neo | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Neomycin marker under RSV promoter. |
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CMV Control lentiviral particles (Puro) |
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| CMV-Null-Puro | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Puromycin marker under RSV promoter. |
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EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV) |
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| LV694975 | ABM | 1.0 ug DNA | EUR 616.8 |
CMV Control lentiviral particles (GFP-Bsd) |
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| CMV-Null-GB | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Blasticidin fusion marker under RSV promoter. |
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CMV Control lentiviral particles (GFP-Puro) |
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| CMV-Null-GP | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Puromycin fusion marker under RSV promoter. |
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CMV Control lentiviral particles (RFP-Bsd) |
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| CMV-Null-RB | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Blasticidin fusion marker under RSV promoter. |
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CMV Control lentiviral particles (RFP-Puro) |
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| CMV-Null-RP | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Puromycin fusion marker under RSV promoter. |
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CMV control lentivirus (Hygro) |
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| CMV-Null-Hygro | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It has the hygromycin selection under RSV promoter. |
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CMV control lentivirus (Zeo) |
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| CMV-Null-Zeo | GenTarget | 1 x107 IFU/ml x 200ul | EUR 418.8 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It has the Zeocin selection under RSV promoter. |
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EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA) |
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| LV709564 | ABM | 1.0 ug DNA | EUR 379.2 |
EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro) |
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| LV709565 | ABM | 1.0 ug DNA | EUR 448.8 |
EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro) |
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| LV709566 | ABM | 1.0 ug DNA | EUR 448.8 |
CMV Control lentiviral particles (Bsd) in PBS |
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| CMV-Null-Bsd-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the blasticidin marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
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CMV Control lentiviral particles (Neo) in PBS |
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| CMV-Null-Neo-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Neomycin marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
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CMV Control lentiviral particles (Puro) in PBS |
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| CMV-Null-Puro-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Puromycin marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
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EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA) |
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| LV694976 | ABM | 1.0 ug DNA | EUR 616.8 |
EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro) |
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| LV694977 | ABM | 1.0 ug DNA | EUR 686.4 |
EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro) |
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| LV694978 | ABM | 1.0 ug DNA | EUR 686.4 |
CMV Control lentiviral particles (GFP-Bsd) in PBS |
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| CMV-Null-GB-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Blasticidin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
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CMV Control lentiviral particles (GFP-Puro) in PBS |
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| CMV-Null-GP-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Puromycin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
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CMV Control lentiviral particles (RFP-Bsd) in PBS |
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| CMV-Null-RB-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Blasticidin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
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CMV Control lentiviral particles (RFP-Puro) in PBS |
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| CMV-Null-RP-PBS | GenTarget | 1 x108 IFU/ml x 200ul | EUR 852 |
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Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Puromycin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution. |
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EBAG9 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC) |
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| LV709567 | ABM | 1.0 ug DNA | EUR 379.2 |
EBAG9 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a) |
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| LV709568 | ABM | 1.0 ug DNA | EUR 379.2 |
ERAF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810237 | ABM | 1.0 ug DNA | EUR 379.2 |
C6orf218 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810243 | ABM | 1.0 ug DNA | EUR 379.2 |
BXDC1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810249 | ABM | 1.0 ug DNA | EUR 379.2 |
C17orf45 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810255 | ABM | 1.0 ug DNA | EUR 379.2 |
FAM86C Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810261 | ABM | 1.0 ug DNA | EUR 379.2 |
C3orf31 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810267 | ABM | 1.0 ug DNA | EUR 379.2 |
C13orf16 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810279 | ABM | 1.0 ug DNA | EUR 379.2 |
C21ORF55 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810285 | ABM | 1.0 ug DNA | EUR 379.2 |
FLJ10357 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810291 | ABM | 1.0 ug DNA | EUR 379.2 |
C13orf3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810297 | ABM | 1.0 ug DNA | EUR 379.2 |
ARL17 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810303 | ABM | 1.0 ug DNA | EUR 379.2 |
HSPC047 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810309 | ABM | 1.0 ug DNA | EUR 379.2 |
C9orf68 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810315 | ABM | 1.0 ug DNA | EUR 379.2 |
C18orf22 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810321 | ABM | 1.0 ug DNA | EUR 379.2 |
KIAA0774 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810327 | ABM | 1.0 ug DNA | EUR 379.2 |
BXDC5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810333 | ABM | 1.0 ug DNA | EUR 379.2 |
IL8RA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810339 | ABM | 1.0 ug DNA | EUR 379.2 |
RBM9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810345 | ABM | 1.0 ug DNA | EUR 379.2 |
FAM62B Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810351 | ABM | 1.0 ug DNA | EUR 379.2 |
BC013798 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810357 | ABM | 1.0 ug DNA | EUR 379.2 |
RTCD1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810363 | ABM | 1.0 ug DNA | EUR 379.2 |
TTC15 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810369 | ABM | 1.0 ug DNA | EUR 379.2 |
RAD51L1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810375 | ABM | 1.0 ug DNA | EUR 379.2 |
TSP50 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810381 | ABM | 1.0 ug DNA | EUR 379.2 |
TMEM22 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810387 | ABM | 1.0 ug DNA | EUR 379.2 |
KTELC1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810393 | ABM | 1.0 ug DNA | EUR 379.2 |
C9orf68 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810399 | ABM | 1.0 ug DNA | EUR 379.2 |
LASS4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810405 | ABM | 1.0 ug DNA | EUR 379.2 |
TMEM49 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810411 | ABM | 1.0 ug DNA | EUR 379.2 |
C2orf24 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810417 | ABM | 1.0 ug DNA | EUR 379.2 |
C1orf62 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810423 | ABM | 1.0 ug DNA | EUR 379.2 |
JMJD5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810429 | ABM | 1.0 ug DNA | EUR 379.2 |
AKD2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810435 | ABM | 1.0 ug DNA | EUR 379.2 |
WDR8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810441 | ABM | 1.0 ug DNA | EUR 379.2 |
LOC90379 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810447 | ABM | 1.0 ug DNA | EUR 379.2 |
SFRS17A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810453 | ABM | 1.0 ug DNA | EUR 379.2 |
FLJ13052 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810459 | ABM | 1.0 ug DNA | EUR 379.2 |
C6orf182 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810465 | ABM | 1.0 ug DNA | EUR 379.2 |
HNRPK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810471 | ABM | 1.0 ug DNA | EUR 379.2 |
C20ORF158 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810477 | ABM | 1.0 ug DNA | EUR 379.2 |
PCTK1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810483 | ABM | 1.0 ug DNA | EUR 379.2 |
IGHGA1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810489 | ABM | 1.0 ug DNA | EUR 379.2 |
C8orf41 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810495 | ABM | 1.0 ug DNA | EUR 379.2 |
C19orf61 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810501 | ABM | 1.0 ug DNA | EUR 379.2 |
C10orf33 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810507 | ABM | 1.0 ug DNA | EUR 379.2 |
KIAA1434 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810513 | ABM | 1.0 ug DNA | EUR 379.2 |
LOC23117 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810519 | ABM | 1.0 ug DNA | EUR 379.2 |
C2orf67 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810525 | ABM | 1.0 ug DNA | EUR 379.2 |
MGC10814 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810531 | ABM | 1.0 ug DNA | EUR 379.2 |
BC006419 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810537 | ABM | 1.0 ug DNA | EUR 379.2 |
C21orf122 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810543 | ABM | 1.0 ug DNA | EUR 379.2 |
BC007926 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810549 | ABM | 1.0 ug DNA | EUR 379.2 |
FLJ38668 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810555 | ABM | 1.0 ug DNA | EUR 379.2 |
MGC13008 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810561 | ABM | 1.0 ug DNA | EUR 379.2 |
C12orf62 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810567 | ABM | 1.0 ug DNA | EUR 379.2 |
BC001867 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810573 | ABM | 1.0 ug DNA | EUR 379.2 |
Sep15 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810579 | ABM | 1.0 ug DNA | EUR 379.2 |
C14orf147 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810585 | ABM | 1.0 ug DNA | EUR 379.2 |
MGC12966 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810591 | ABM | 1.0 ug DNA | EUR 379.2 |
LOC113386 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810597 | ABM | 1.0 ug DNA | EUR 379.2 |
LOC80154 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810603 | ABM | 1.0 ug DNA | EUR 379.2 |
LOC100132167 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810609 | ABM | 1.0 ug DNA | EUR 379.2 |
C4orf42 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810615 | ABM | 1.0 ug DNA | EUR 379.2 |
Selk Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810621 | ABM | 1.0 ug DNA | EUR 379.2 |
MGC21881 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810627 | ABM | 1.0 ug DNA | EUR 379.2 |
MGC13057 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810633 | ABM | 1.0 ug DNA | EUR 379.2 |
C18orf20 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810639 | ABM | 1.0 ug DNA | EUR 379.2 |
CXorf50B Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810645 | ABM | 1.0 ug DNA | EUR 379.2 |
C13orf36 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810651 | ABM | 1.0 ug DNA | EUR 379.2 |
NDR1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810657 | ABM | 1.0 ug DNA | EUR 379.2 |
C20orf30 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810663 | ABM | 1.0 ug DNA | EUR 379.2 |
C20orf30 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810669 | ABM | 1.0 ug DNA | EUR 379.2 |
Magmas Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810675 | ABM | 1.0 ug DNA | EUR 379.2 |
C6orf168 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810681 | ABM | 1.0 ug DNA | EUR 379.2 |
Dram Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810687 | ABM | 1.0 ug DNA | EUR 379.2 |
FLJ20897 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810693 | ABM | 1.0 ug DNA | EUR 379.2 |
FLJ14107 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810699 | ABM | 1.0 ug DNA | EUR 379.2 |
ZD52F10 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
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| LV810705 | ABM | 1.0 ug DNA | EUR 379.2 |
SEDLP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810711 | ABM | 1.0 ug DNA | EUR 379.2 |
C14orf48 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810717 | ABM | 1.0 ug DNA | EUR 379.2 |
C6orf35 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810723 | ABM | 1.0 ug DNA | EUR 379.2 |
MGC34034 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810729 | ABM | 1.0 ug DNA | EUR 379.2 |
C15ORF15 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810735 | ABM | 1.0 ug DNA | EUR 379.2 |
LOC339047 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810741 | ABM | 1.0 ug DNA | EUR 379.2 |
MGC31957 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810747 | ABM | 1.0 ug DNA | EUR 379.2 |
LOC153328 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810753 | ABM | 1.0 ug DNA | EUR 379.2 |
C3orf34 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810759 | ABM | 1.0 ug DNA | EUR 379.2 |
RANGNRF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810765 | ABM | 1.0 ug DNA | EUR 379.2 |
RANGNRF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810771 | ABM | 1.0 ug DNA | EUR 379.2 |
C18orf10 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810777 | ABM | 1.0 ug DNA | EUR 379.2 |
NAT13 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810783 | ABM | 1.0 ug DNA | EUR 379.2 |
C9orf61 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810789 | ABM | 1.0 ug DNA | EUR 379.2 |
FKSG24 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810795 | ABM | 1.0 ug DNA | EUR 379.2 |
C3orf60 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810801 | ABM | 1.0 ug DNA | EUR 379.2 |
C2orf7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810807 | ABM | 1.0 ug DNA | EUR 379.2 |
RWDD4A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810813 | ABM | 1.0 ug DNA | EUR 379.2 |
SAPS3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810819 | ABM | 1.0 ug DNA | EUR 379.2 |
Hdgfrp3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810825 | ABM | 1.0 ug DNA | EUR 379.2 |
MOBKL2B Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810837 | ABM | 1.0 ug DNA | EUR 379.2 |
RAB39 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810843 | ABM | 1.0 ug DNA | EUR 379.2 |
C10orf58 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810849 | ABM | 1.0 ug DNA | EUR 379.2 |
PI31 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810855 | ABM | 1.0 ug DNA | EUR 379.2 |
C1orf142 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810861 | ABM | 1.0 ug DNA | EUR 379.2 |
VPS24 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810867 | ABM | 1.0 ug DNA | EUR 379.2 |
AK3L1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810873 | ABM | 1.0 ug DNA | EUR 379.2 |
FLJ25770 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810879 | ABM | 1.0 ug DNA | EUR 379.2 |
BC008939 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810885 | ABM | 1.0 ug DNA | EUR 379.2 |
GPR175 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810891 | ABM | 1.0 ug DNA | EUR 379.2 |
C1orf190 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810897 | ABM | 1.0 ug DNA | EUR 379.2 |
C20orf12 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810903 | ABM | 1.0 ug DNA | EUR 379.2 |
C18orf55 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810909 | ABM | 1.0 ug DNA | EUR 379.2 |
SFRS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810915 | ABM | 1.0 ug DNA | EUR 379.2 |
ZNF509 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810921 | ABM | 1.0 ug DNA | EUR 379.2 |
FRAG1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810927 | ABM | 1.0 ug DNA | EUR 379.2 |
Nip30 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810933 | ABM | 1.0 ug DNA | EUR 379.2 |
C18orf24 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810939 | ABM | 1.0 ug DNA | EUR 379.2 |
PLUNC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810945 | ABM | 1.0 ug DNA | EUR 379.2 |
UNC84A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810951 | ABM | 1.0 ug DNA | EUR 379.2 |
C20orf39 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810957 | ABM | 1.0 ug DNA | EUR 379.2 |
C1orf89 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810963 | ABM | 1.0 ug DNA | EUR 379.2 |
Seli Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810969 | ABM | 1.0 ug DNA | EUR 379.2 |
TINP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810975 | ABM | 1.0 ug DNA | EUR 379.2 |
SRrp35 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810981 | ABM | 1.0 ug DNA | EUR 379.2 |
C1orf71 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810987 | ABM | 1.0 ug DNA | EUR 379.2 |
HEL308 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810993 | ABM | 1.0 ug DNA | EUR 379.2 |
WDR42A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV810999 | ABM | 1.0 ug DNA | EUR 379.2 |
C12orf24 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811005 | ABM | 1.0 ug DNA | EUR 379.2 |
C9orf30 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811011 | ABM | 1.0 ug DNA | EUR 379.2 |
DIMT1L Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811017 | ABM | 1.0 ug DNA | EUR 379.2 |
FAM164C Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811023 | ABM | 1.0 ug DNA | EUR 379.2 |
CCDC5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811029 | ABM | 1.0 ug DNA | EUR 379.2 |
C14orf104 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811035 | ABM | 1.0 ug DNA | EUR 379.2 |
MUDENG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811041 | ABM | 1.0 ug DNA | EUR 379.2 |
Sc4mol Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811047 | ABM | 1.0 ug DNA | EUR 379.2 |
HNRPC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811053 | ABM | 1.0 ug DNA | EUR 379.2 |
HNRPC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811059 | ABM | 1.0 ug DNA | EUR 379.2 |
MCART1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811065 | ABM | 1.0 ug DNA | EUR 379.2 |
CDC2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811071 | ABM | 1.0 ug DNA | EUR 379.2 |
C5orf35 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811077 | ABM | 1.0 ug DNA | EUR 379.2 |
C1orf102 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811083 | ABM | 1.0 ug DNA | EUR 379.2 |
SGEF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
| LV811089 | ABM | 1.0 ug DNA | EUR 379.2 |
The Intracellular Area of CD40 is a Potent Costimulatory Component in Chimeric Antigen Receptors
The costimulatory domains included into second-generation and third-generation chimeric antigen receptors (CARs) strongly affect CAR-T-cell operate. Right here, we explored second-generation and third-generation CARs harboring the signaling area of the CD40 receptor as a brand new costimulatory aspect as compared with related CARs carrying the 4-1BB area. In CARs of each generations, CD40 was stronger than 4-1BB in triggering the NF-κB signaling pathway.
In human T cells from 2 donors, CD40 was akin to 4-1BB in upregulating costimulatory and activation markers, inducing proinflammatory cytokine secretion and mediating goal cell killing. Apparently, variations within the response sample of T cells from the two donors with respect to CD40 and 4-1BB have been evident. We conclude that in human T cells, the CD40 signaling area is a potent costimulatory aspect in each second-generation and third-generation CARs.
A Systematic Overview of the Function of Chimeric Antigen Receptor T (CAR-T) Cell Remedy within the Therapy of Strong Tumors
Chimeric antigen receptor T (CAR-T) cell remedy makes use of sufferers’ personal T lymphocytes which might be engineered to assault most cancers cells. It’s Meals and Drug Administration (FDA)-approved in numerous hematological malignancies and presently being evaluated in strong cancers in early section research. We did a scientific overview consisting of 15 potential medical trials (n=159) evaluating CAR-T cells in strong cancers. Early section trials confirmed promising response charges in ovarian epithelial most cancers (100%), human epidermal progress issue receptor 2 (HER2)-positive sarcoma (67%), epidermal progress issue receptor (EGFR)-positive biliary tract most cancers (65%), superior gastric/pancreatic most cancers (82%), hepatocellular carcinoma (67%), and colorectal most cancers (70%).
The median general response throughout all malignancies was 62% (vary 17%-100%). Median progression-free survival and general survival weren’t reached in most trials. Cytokine launch syndrome was seen in just one affected person with cholangiocarcinoma who obtained EGFR-specific CAR-T cell remedy. Though survival knowledge continues to be not mature, CAR-T cell remedy in strong malignancies did present encouraging response charges and was well-tolerated.
Variations in lymphoma sufferers between chimeric antigen receptor T-cell remedy trials and the overall inhabitants
Chimeric antigen receptor (CAR)-T cell therapies seem to be promising therapies for non-Hodgkin’s and B-cell lymphoma. Nonetheless, a number of CAR-T therapies accredited by the US Meals and Drug Administration have solely been examined for efficacy in comparatively few single-arm medical trials with small pattern sizes. We sought to look at the variations between sufferers in these trials and the overall inhabitants of sufferers with non-Hodgkin’s and B-cell lymphoma. 5 hundred and twenty-two sufferers from 15 CAR-T trials present in a scientific overview and 417,492 sufferers from the Surveillance, Epidemiology, and Finish Outcomes (SEER) Program database have been in contrast.
CAR-T research individuals seemed to be youthful (46.7% beneath 70 years previous vs. 42.2%), extra male (68.0% vs. 55.7%), and adopted for a shorter time period in comparison with sufferers within the SEER inhabitants (imply [M] 45.6 months, 95% confidence interval [CI] 17.7 to 63.three months follow-up vs. M 57.1 months, 95% CI 57.Zero to 57.three months survival). CAR-T research individuals might differ considerably from the overall inhabitants of sufferers with non-Hodgkin’s and B-cell lymphoma. Effectiveness of CAR-T therapies within the common inhabitants of lymphoma sufferers might differ from effectiveness demonstrated in trials. Newly created CAR-T affected person registries are important to establishing population-level effectiveness of the therapies.
Recombinant Human ITGB1 Protein, His, E.coli-2ug |
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| QP12462-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ITGB1 Protein, His, E.coli-5ug |
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| QP12462-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human ITGB1 Protein, His, E.coli-1mg |
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| QP12462-HIS-EC-1mg | EnQuireBio | 1mg | EUR 3308.4 |
ITGB1 protein (His tag) |
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| 80R-3617 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Purified recombinant ITGB1 protein (His tag) |
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Human Integrin Beta 1 (ITGb1) ELISA Kit |
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| DLR-ITGb1-Hu-48T | DL Develop | 48T | EUR 597.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Beta 1 (ITGb1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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Human Integrin Beta 1 (ITGb1) ELISA Kit |
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| DLR-ITGb1-Hu-96T | DL Develop | 96T | EUR 776.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Integrin Beta 1 (ITGb1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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Human Integrin Beta 1 (ITGb1) ELISA Kit |
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| RD-ITGb1-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 600 |
Human Integrin Beta 1 (ITGb1) ELISA Kit |
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| RD-ITGb1-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 830.4 |
Human Integrin Beta 1 (ITGb1) ELISA Kit |
|||
| RDR-ITGb1-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 626.4 |
Human Integrin Beta 1 (ITGb1) ELISA Kit |
|||
| RDR-ITGb1-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 868.8 |
Recombinant Human ITGB1 Protein, His, Insect-1mg |
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| QP12462-HIS-INSECT-1mg | EnQuireBio | 1mg | EUR 6301.2 |
XMIR-21 RNA oligo miRNA-21-5p with Xmotif |
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| XMIR-21 | SBI | 10 rxn | EUR 525.6 |
Recombinant (E.coli) Human CD40 (aa: 21-193, His Tag, >95% Pure) |
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| HCD4015-N-10 | Alpha Diagnostics | 10 ug | EUR 343.2 |
AXMIR-21 RNA oligo anti-miRNA-21-5p with Xmotif |
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| AXMIR-21 | SBI | 10 reactions | EUR 525.6 |
ICP Quality Control Standard 21 |
|||
| QC-21 | Scientific Laboratory Supplies | 125ML | EUR 337.44 |
Recombinant (E.Coli, His-tag) Human Syndecan-4, His-tag |
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| RP-993 | Alpha Diagnostics | 10 ug | EUR 270 |
Recombinant (E.coli) Rat CD40 (aa: 21-193, His Tag, >95% Pure) |
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| RCD4015-N-10 | Alpha Diagnostics | 10 ug | EUR 255.6 |
FGF-21 Fibroblast Growth Factor-21 Human Recombinant Protein, His Tag |
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| PROTQ9NSA1 | BosterBio | Regular: 50ug | EUR 380.4 |
|
Description: Fibroblast Growth Factor -21 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 202 amino acids (29-209) and having a molecular mass of 21.6 kDa (molecular weight on SDS-PAGE will appear higher). ;The FGF-21 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. |
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Recombinant (E.Coli, His-tag) Human HTRA2 |
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| RP-413 | Alpha Diagnostics | 10 ug | EUR 270 |
Recombinant (E.Coli, His-tag) Human STAT1 |
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| RP-722 | Alpha Diagnostics | 10 ug | EUR 343.2 |
Recombinant (E.Coli, His-tag) Human S100b |
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| RP-774 | Alpha Diagnostics | 10 ug | EUR 343.2 |
Recombinant (E.Coli, His-tag) Human Osteocrin |
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| RP-868 | Alpha Diagnostics | 10 ug | EUR 343.2 |
Recombinant (E.Coli, His-tag) Human CD29 |
|||
| RP-915 | Alpha Diagnostics | 2 ug | EUR 416.4 |
Recombinant (E.Coli, His-tag) Human Geminin |
|||
| RP-989 | Alpha Diagnostics | 5 ug | EUR 196.8 |
Recombinant Human Fibroblast Growth Factor-21, His Tag |
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| 7-00385 | CHI Scientific | 10µg | Ask for price |
Recombinant Human Fibroblast Growth Factor-21, His Tag |
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| 7-00386 | CHI Scientific | 50µg | Ask for price |
Recombinant Human Fibroblast Growth Factor-21, His Tag |
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| 7-00387 | CHI Scientific | 1mg | Ask for price |
Recombinant E.coli LACTB Protein, His, E.coli-20ug |
|||
| QP12522-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant E.coli LACTB Protein, His, E.coli-5ug |
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| QP12522-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
XMIRXpress lentivector miRNA-21-5p with Xmotif |
|||
| XMIRXP-21 | SBI | 10 ug | EUR 812.4 |
Recombinant (E.Coli, His-tag) Human Ubiquitin Conjugating enzyme 7, His-tag |
|||
| RP-425 | Alpha Diagnostics | 10 ug | EUR 270 |
Recombinant Human ACPP Protein, His, E.coli-100ug |
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| QP10946-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human ACPP Protein, His, E.coli-10ug |
|||
| QP10946-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ACPP Protein, His, E.coli-1mg |
|||
| QP10946-HIS-1mg | EnQuireBio | 1mg | EUR 4386 |
Recombinant Human ACPP Protein, His, E.coli-20ug |
|||
| QP10946-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human ACPP Protein, His, E.coli-2ug |
|||
| QP10946-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ACPP Protein, His, E.coli-5ug |
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| QP10946-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human ADAM10 Protein, His, E.coli-10ug |
|||
| QP10961-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ADAM10 Protein, His, E.coli-1mg |
|||
| QP10961-HIS-1mg | EnQuireBio | 1mg | EUR 5821.2 |
Recombinant Human ADAM10 Protein, His, E.coli-1ug |
|||
| QP10961-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human ADAM10 Protein, His, E.coli-2ug |
|||
| QP10961-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ADAM10 Protein, His, E.coli-50ug |
|||
| QP10961-HIS-50ug | EnQuireBio | 50ug | EUR 1513.2 |
Recombinant Human ADAM10 Protein, His, E.coli-5ug |
|||
| QP10961-HIS-5ug | EnQuireBio | 5ug | EUR 241.2 |
Recombinant Human ADH1A Protein, His, E.coli-10ug |
|||
| QP10966-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ADH1A Protein, His, E.coli-20ug |
|||
| QP10966-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human ADH1A Protein, His, E.coli-2ug |
|||
| QP10966-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ADH1A Protein, His, E.coli-5ug |
|||
| QP10966-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human Adipsin Protein, His, E.coli-10ug |
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| QP10969-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human Adipsin Protein, His, E.coli-20ug |
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| QP10969-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human Adipsin Protein, His, E.coli-2ug |
|||
| QP10969-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human Adipsin Protein, His, E.coli-5ug |
|||
| QP10969-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human AKR1D1 Protein, His, E.coli-20ug |
|||
| QP10995-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human AKR1D1 Protein, His, E.coli-5ug |
|||
| QP10995-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human AMBP Protein, His, E.coli-10ug |
|||
| QP11009-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human AMBP Protein, His, E.coli-1mg |
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| QP11009-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human AMBP Protein, His, E.coli-2ug |
|||
| QP11009-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ANGPTL3 Protein, His, E.coli-100ug |
|||
| QP11018-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human ANGPTL3 Protein, His, E.coli-1mg |
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| QP11018-HIS-1mg | EnQuireBio | 1mg | EUR 5821.2 |
Recombinant Human APOA5 Protein, His, E.coli-2ug |
|||
| QP11046-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ATP1B1 Protein, His, E.coli-10ug |
|||
| QP11104-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ATP1B1 Protein, His, E.coli-20ug |
|||
| QP11104-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human ATP1B1 Protein, His, E.coli-2ug |
|||
| QP11104-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ATP1B1 Protein, His, E.coli-5ug |
|||
| QP11104-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human ATP1B2 Protein, His, E.coli-10ug |
|||
| QP11105-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human ATP1B2 Protein, His, E.coli-20ug |
|||
| QP11105-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human ATP1B2 Protein, His, E.coli-2ug |
|||
| QP11105-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human ATP1B2 Protein, His, E.coli-5ug |
|||
| QP11105-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human AZGP1 Protein, His, E.coli-1mg |
|||
| QP11114-HIS-1mg | EnQuireBio | 1mg | EUR 4386 |
Recombinant Human AZGP1 Protein, His, E.coli-20ug |
|||
| QP11114-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human AZGP1 Protein, His, E.coli-5ug |
|||
| QP11114-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human B2M Protein, His, E.coli-1ug |
|||
| QP11117-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human B2M Protein, His, E.coli-50ug |
|||
| QP11117-HIS-50ug | EnQuireBio | 50ug | EUR 1393.2 |
Recombinant Human B2M Protein, His, E.coli-5ug |
|||
| QP11117-HIS-5ug | EnQuireBio | 5ug | EUR 241.2 |
Recombinant Human BIRC7 Protein, His, E.coli-20ug |
|||
| QP11164-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human BIRC7 Protein, His, E.coli-5ug |
|||
| QP11164-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human IGFBP7 Protein, His, E.coli-100ug |
|||
| QP12384-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human IGFBP7 Protein, His, E.coli-10ug |
|||
| QP12384-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human IGFBP7 Protein, His, E.coli-2ug |
|||
| QP12384-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human IL13RA2 Protein, His, E.coli-10ug |
|||
| QP12406-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human IL13RA2 Protein, His, E.coli-20ug |
|||
| QP12406-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human IL13RA2 Protein, His, E.coli-2ug |
|||
| QP12406-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human IL13RA2 Protein, His, E.coli-5ug |
|||
| QP12406-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human KLF4 Protein, His, E.coli-20ug |
|||
| QP12498-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLF4 Protein, His, E.coli-5ug |
|||
| QP12498-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human KLK15 Protein, His, E.coli-1mg |
|||
| QP12504-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human KLK15 Protein, His, E.coli-1ug |
|||
| QP12504-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human KLK15 Protein, His, E.coli-20ug |
|||
| QP12504-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLK15 Protein, His, E.coli-50ug |
|||
| QP12504-HIS-50ug | EnQuireBio | 50ug | EUR 1513.2 |
Recombinant Human KLK2 Protein, His, E.coli-1mg |
|||
| QP12505-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human KLK2 Protein, His, E.coli-1ug |
|||
| QP12505-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human KLK2 Protein, His, E.coli-20ug |
|||
| QP12505-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLK2 Protein, His, E.coli-50ug |
|||
| QP12505-HIS-50ug | EnQuireBio | 50ug | EUR 1393.2 |
Recombinant Human KLK3 Protein, His, E.coli-1mg |
|||
| QP12506-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human KLK3 Protein, His, E.coli-20ug |
|||
| QP12506-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLK3 Protein, His, E.coli-5ug |
|||
| QP12506-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human KLK5 Protein, His, E.coli-100ug |
|||
| QP12507-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human KLK5 Protein, His, E.coli-1mg |
|||
| QP12507-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human KLRB1 Protein, His, E.coli-1mg |
|||
| QP12508-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human KLRB1 Protein, His, E.coli-1ug |
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| QP12508-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human KLRB1 Protein, His, E.coli-20ug |
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| QP12508-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human KLRB1 Protein, His, E.coli-50ug |
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| QP12508-HIS-50ug | EnQuireBio | 50ug | EUR 1513.2 |
Recombinant Human LHRH Protein, His, E.coli-1mg |
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| QP12569-HIS-1mg | EnQuireBio | 1mg | EUR 4386 |
Recombinant Human LHRH Protein, His, E.coli-20ug |
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| QP12569-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human LHRH Protein, His, E.coli-5ug |
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| QP12569-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human LIN28 Protein, His, E.coli-10ug |
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| QP12571-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human LIN28 Protein, His, E.coli-2ug |
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| QP12571-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human LIPG Protein, His, E.coli-10ug |
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| QP12577-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human LIPG Protein, His, E.coli-20ug |
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| QP12577-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human LIPG Protein, His, E.coli-2ug |
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| QP12577-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human LIPG Protein, His, E.coli-5ug |
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| QP12577-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human LPL Protein, His, E.coli-10ug |
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| QP12581-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human LPL Protein, His, E.coli-1mg |
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| QP12581-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human LPL Protein, His, E.coli-2ug |
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| QP12581-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human LRG1 Protein, His, E.coli-1mg |
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| QP12583-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human LRG1 Protein, His, E.coli-20ug |
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| QP12583-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human LRG1 Protein, His, E.coli-5ug |
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| QP12583-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human LUM Protein, His, E.coli-10ug |
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| QP12598-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human LUM Protein, His, E.coli-20ug |
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| QP12598-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human LUM Protein, His, E.coli-2ug |
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| QP12598-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human LUM Protein, His, E.coli-5ug |
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| QP12598-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human LYVE1 Protein, His, E.coli-1mg |
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| QP12609-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human MAPK1 Protein, His, E.coli-1mg |
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| QP12639-HIS-1mg | EnQuireBio | 1mg | EUR 2774.4 |
Recombinant Human MAPK1 Protein, His, E.coli-25ug |
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| QP12639-HIS-25ug | EnQuireBio | 25ug | EUR 241.2 |
Recombinant Human MAPK1 Protein, His, E.coli-5ug |
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| QP12639-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human MFAP4 Protein, His, E.coli-10ug |
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| QP12691-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human MFAP4 Protein, His, E.coli-20ug |
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| QP12691-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human MFAP4 Protein, His, E.coli-2ug |
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| QP12691-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human MFAP4 Protein, His, E.coli-5ug |
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| QP12691-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human NARS Protein, His, E.coli-100ug |
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| QP12794-HIS-100ug | EnQuireBio | 100ug | EUR 1513.2 |
Recombinant Human NARS Protein, His, E.coli-1mg |
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| QP12794-HIS-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human NXPH1 Protein, His, E.coli-10ug |
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| QP12912-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human NXPH1 Protein, His, E.coli-20ug |
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| QP12912-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human NXPH1 Protein, His, E.coli-2ug |
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| QP12912-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human NXPH1 Protein, His, E.coli-5ug |
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| QP12912-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human PDCD1LG2 Protein, His, E.coli-10ug |
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| QP12985-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human PDCD1LG2 Protein, His, E.coli-20ug |
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| QP12985-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PDCD1LG2 Protein, His, E.coli-2ug |
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| QP12985-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human PDCD1LG2 Protein, His, E.coli-5ug |
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| QP12985-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human PEDF Protein, His, E.coli-1mg |
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| QP13005-HIS-1mg | EnQuireBio | 1mg | EUR 3667.2 |
Recombinant Human PEDF Protein, His, E.coli-20ug |
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| QP13005-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PEDF Protein, His, E.coli-5ug |
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| QP13005-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human PSG1 Protein, His, E.coli-10ug |
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| QP13179-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human PSG1 Protein, His, E.coli-20ug |
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| QP13179-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PSG1 Protein, His, E.coli-2ug |
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| QP13179-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human PSG1 Protein, His, E.coli-5ug |
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| QP13179-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human PSG5 Protein, His, E.coli-1mg |
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| QP13180-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human PSG5 Protein, His, E.coli-1ug |
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| QP13180-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human PSG5 Protein, His, E.coli-20ug |
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| QP13180-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PSG5 Protein, His, E.coli-50ug |
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| QP13180-HIS-50ug | EnQuireBio | 50ug | EUR 1393.2 |
Recombinant Human PTEN Protein, His, E.coli-100ug |
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| QP13199-HIS-0.1mg | EnQuireBio | 100ug | EUR 1698 |
Recombinant Human PTEN Protein, His, E.coli-1ug |
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| QP13199-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human PTX3 Protein, His, E.coli-10ug |
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| QP13217-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human PTX3 Protein, His, E.coli-20ug |
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| QP13217-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human PTX3 Protein, His, E.coli-2ug |
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| QP13217-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human PTX3 Protein, His, E.coli-5ug |
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| QP13217-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human RBP4 Protein, His, E.coli-10ug |
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| QP13283-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human RBP4 Protein, His, E.coli-2ug |
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| QP13283-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human REN Protein, His, E.coli-10ug |
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| QP13296-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human REN Protein, His, E.coli-25ug |
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| QP13296-HIS-25ug | EnQuireBio | 25ug | EUR 241.2 |
Recombinant Human REN Protein, His, E.coli-2ug |
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| QP13296-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human REN Protein, His, E.coli-5ug |
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| QP13296-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human RLBP1 Protein, His, E.coli-10ug |
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| QP13321-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human RLBP1 Protein, His, E.coli-20ug |
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| QP13321-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human RLBP1 Protein, His, E.coli-2ug |
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| QP13321-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human RLBP1 Protein, His, E.coli-5ug |
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| QP13321-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human RLN2 Protein, His, E.coli-1mg |
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| QP13322-HIS-1mg | EnQuireBio | 1mg | EUR 3308.4 |
Recombinant Human RLN2 Protein, His, E.coli-1ug |
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| QP13322-HIS-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human RLN2 Protein, His, E.coli-25ug |
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| QP13322-HIS-25ug | EnQuireBio | 25ug | EUR 241.2 |
Recombinant Human RLN2 Protein, His, E.coli-50ug |
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| QP13322-HIS-50ug | EnQuireBio | 50ug | EUR 1273.2 |
Recombinant Human RNASE3 Protein, His, E.coli-10ug |
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| QP13323-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human RNASE3 Protein, His, E.coli-20ug |
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| QP13323-HIS-20ug | EnQuireBio | 20ug | EUR 241.2 |
Recombinant Human RNASE3 Protein, His, E.coli-2ug |
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| QP13323-HIS-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human RNASE3 Protein, His, E.coli-5ug |
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| QP13323-HIS-5ug | EnQuireBio | 5ug | EUR 186 |
Recombinant Human S100A8 Protein, His, E.coli-10ug |
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| QP13399-HIS-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human S100A8 Protein, His, E.coli-2ug |
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| QP13399-HIS-2ug | EnQuireBio | 2ug | EUR 186 |