ultrasonic-scientific

Soluble Antibody Stimulation as Revealed by BOOST Phosphotyrosine Proteomics

Are chimeric antigen receptor T cells (CAR-T cells) the long run in immunotherapy for autoimmune illnesses?

Goal: CAR-T cell remedy has revolutionized the remedy of oncological illnesses, and potential makes use of in autoimmune illnesses have just lately been described. The overview goals to combine the accessible knowledge on remedy with CAR-T cells, emphasizing autoimmune illnesses, to find out therapeutic advances and their doable future medical applicability in autoimmunity.

Supplies and strategies: A search was carried out in PubMed with the key phrases “Chimeric Antigen Receptor” and “CART cell”. The paperwork of curiosity have been chosen, and a essential overview of the data was carried out.

Outcomes: Within the remedy of autoimmune illnesses, in preclinical fashions, three completely different mobile methods have been used, which embody Chimeric antigen receptor T cells, Chimeric autoantibody receptor T cells, and Chimeric antigen receptor in regulatory T lymphocytes. All three sorts of remedy have been efficient. The potential antagonistic results inside them, cytokine launch syndrome, mobile toxicity and neurotoxicity should all the time be stored in thoughts.

Conclusions: Though info in people just isn’t but accessible, preclinical fashions of CAR-T cells within the remedy of autoimmune illnesses present promising outcomes, in order that sooner or later, they could turn out to be a helpful and efficient remedy within the remedy of those pathologies.

 

Ovalbumin Antigen-Particular Activation of Human T Cell Receptor Carefully Resembles Soluble Antibody Stimulation as Revealed by BOOST Phosphotyrosine Proteomics

Activation of the T cell receptor (TCR) results in a community of early signaling predominantly orchestrated by tyrosine phosphorylation in T cells. The TCR is usually activated utilizing soluble anti-TCR antibodies, however this method just isn’t antigen-specific. Alternatively, activating the TCR utilizing particular antigens of a spread of binding affinities within the type of a peptide-major histocompatibility advanced (pMHC) is presumed to be extra physiological. Nonetheless, because of the lack of wide-scale phosphotyrosine (pTyr) proteomic research straight evaluating anti-TCR antibodies and pMHC, a complete definition of those activated states stays enigmatic.

Elucidation of the tyrosine phosphoproteome utilizing quantitative pTyr proteomics permits a greater understanding of the distinctive options of those activating brokers and the position of ligand binding affinity on signaling. Right here, we apply the just lately established Broad-spectrum Optimization Of Selective Triggering (BOOST) to look at perturbations in tyrosine phosphorylation of human TCR triggered by anti-TCR antibodies and pMHC. Our knowledge reveal that high-affinity ovalbumin (OVA) pMHC activation of the human TCR triggers a largely related, albeit doubtlessly stronger, pTyr-mediated signaling regulatory axis in comparison with the anti-TCR antibody. The signaling output ensuing from OVA pMHC variants correlates properly with their weaker affinities, enabling affinity-tunable management of signaling energy. Collectively, we offer a framework for making use of BOOST to match pTyr-mediated signaling pathways of human T cells activated in an antigen-independent and antigen-specific method.

Bilateral anterior cerebral artery occlusion following CD19- and BCMA-targeted chimeric antigen receptor T-cell remedy for a myeloma affected person

Chimeric antigen receptor T (CAR-T)-cell remedy is a promising remedy for relapsed/refractory a number of myeloma (RRMM). In our earlier report, CD19- and BCMA-targeted CAR-T co-administration was related to a excessive response fee. Though cytokine launch syndrome (CRS) and neurotoxicity are frequent issues following CAR-T remedy, cerebral infarction is never reported as a CAR-T-related complication. We reported a 73-year-old feminine MM affected person who obtained CD19- and BCMA-targeted CAR-T for refractory illness.

Her illness responded to CAR-T remedy, however she developed neurological signs following CRS. Cranial CT and MRI demonstrated a number of cerebral infarctions and bilateral anterior cerebral artery (ACA) occlusion. We propose that cerebral infarction aside from CAR-T-related neurotoxicity is the underlying reason behind irregular neuropsychological signs, and diagnostic imaging assessments must be actively carried out to exclude ischemic cerebrovascular occasions.

ultrasonic-scientific
ultrasonic-scientific

EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV709564 1.0 ug DNA
EUR 379.2

EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV709565 1.0 ug DNA
EUR 448.8

EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV709566 1.0 ug DNA
EUR 448.8

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV694976 1.0 ug DNA
EUR 616.8

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV694977 1.0 ug DNA
EUR 686.4

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV694978 1.0 ug DNA
EUR 686.4

EBAG9 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

LV709567 1.0 ug DNA
EUR 379.2

EBAG9 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV709568 1.0 ug DNA
EUR 379.2

EBAG9 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV694979 1.0 ug DNA
EUR 616.8

EBAG9 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV694980 1.0 ug DNA
EUR 616.8

P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739457 1.0 ug DNA Ask for price

MS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV734267 1.0 ug DNA Ask for price

NA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV735845 1.0 ug DNA Ask for price

NP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV814299 1.0 ug DNA
EUR 540

CS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709011 1.0 ug DNA
EUR 379.2

HP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703719 1.0 ug DNA
EUR 540

C5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704421 1.0 ug DNA
EUR 540

S7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747677 1.0 ug DNA Ask for price

IV Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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NM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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XM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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XS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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MAA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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MCO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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MEB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732671 1.0 ug DNA Ask for price

mF4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732743 1.0 ug DNA Ask for price

GCY Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV726557 1.0 ug DNA Ask for price

FND Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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ST2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749651 1.0 ug DNA
EUR 686.4

ST3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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ST4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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ST8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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TDD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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THM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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DM1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723179 1.0 ug DNA Ask for price

DWS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723515 1.0 ug DNA Ask for price

EBM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723683 1.0 ug DNA Ask for price

EGI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723929 1.0 ug DNA Ask for price

F7R Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724757 1.0 ug DNA Ask for price

MLS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733631 1.0 ug DNA Ask for price

MOK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733685 1.0 ug DNA Ask for price

MPE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733739 1.0 ug DNA Ask for price

MSD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV734285 1.0 ug DNA Ask for price

CPP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV759281 1.0 ug DNA
EUR 2148

CPQ Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV759287 1.0 ug DNA
EUR 686.4

TOC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV750677 1.0 ug DNA Ask for price

PB1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV815385 1.0 ug DNA
EUR 540

UTX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV814419 1.0 ug DNA
EUR 540

AEN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707157 1.0 ug DNA
EUR 379.2

AEN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707163 1.0 ug DNA
EUR 379.2

AGK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707187 1.0 ug DNA
EUR 379.2

ALB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707271 1.0 ug DNA
EUR 379.2

ANG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707325 1.0 ug DNA
EUR 379.2

ATM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707655 1.0 ug DNA
EUR 379.2

BID Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707847 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707871 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707877 1.0 ug DNA
EUR 379.2

CA8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708255 1.0 ug DNA
EUR 379.2

CA8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708261 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708339 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708345 1.0 ug DNA
EUR 379.2

CGA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708669 1.0 ug DNA
EUR 379.2

CKB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708753 1.0 ug DNA
EUR 379.2

CRK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708987 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708993 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708999 1.0 ug DNA
EUR 379.2

DTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709467 1.0 ug DNA
EUR 379.2

EVL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709839 1.0 ug DNA
EUR 379.2

PIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713469 1.0 ug DNA
EUR 379.2

PTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713985 1.0 ug DNA
EUR 379.2

RGR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV714303 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715317 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715323 1.0 ug DNA
EUR 379.2

Syk Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715605 1.0 ug DNA
EUR 379.2

TK1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715875 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710247 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710253 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710259 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710265 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710271 1.0 ug DNA
EUR 379.2

FUZ Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710289 1.0 ug DNA
EUR 379.2

GIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710403 1.0 ug DNA
EUR 379.2

GRN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710661 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710829 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710835 1.0 ug DNA
EUR 379.2

HYI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711141 1.0 ug DNA
EUR 379.2

JTB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711555 1.0 ug DNA
EUR 379.2

LBH Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711897 1.0 ug DNA
EUR 379.2

LTF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712071 1.0 ug DNA
EUR 379.2

LUM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712083 1.0 ug DNA
EUR 379.2

LXN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712089 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712167 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712173 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712179 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712185 1.0 ug DNA
EUR 379.2

MPI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712365 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV701979 1.0 ug DNA
EUR 540

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703479 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703695 1.0 ug DNA
EUR 540

LY9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703815 1.0 ug DNA
EUR 540

FGA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704103 1.0 ug DNA
EUR 540

NNT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704253 1.0 ug DNA
EUR 379.2

LY9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705291 1.0 ug DNA
EUR 540

DUT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705459 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705585 1.0 ug DNA
EUR 540

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705639 1.0 ug DNA
EUR 540

FTO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705999 1.0 ug DNA
EUR 540

MIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV706503 1.0 ug DNA
EUR 540

C8A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV702501 1.0 ug DNA
EUR 540

SLN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV702969 1.0 ug DNA
EUR 540

TTK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716385 1.0 ug DNA
EUR 379.2

UBB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716529 1.0 ug DNA
EUR 379.2

WAC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716727 1.0 ug DNA
EUR 379.2

AFA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718313 1.0 ug DNA Ask for price

AIC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718391 1.0 ug DNA Ask for price

AOM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718865 1.0 ug DNA Ask for price

ATD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV719171 1.0 ug DNA Ask for price

NF2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712731 1.0 ug DNA
EUR 379.2

NMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712773 1.0 ug DNA
EUR 379.2

OAT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712983 1.0 ug DNA
EUR 379.2

OS9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713019 1.0 ug DNA
EUR 379.2

CCT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV720665 1.0 ug DNA Ask for price

CCV Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV720719 1.0 ug DNA Ask for price

CHR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721169 1.0 ug DNA Ask for price

CMM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721403 1.0 ug DNA Ask for price

CNC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721451 1.0 ug DNA Ask for price

COP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721595 1.0 ug DNA Ask for price

CRG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721781 1.0 ug DNA Ask for price

CRS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721793 1.0 ug DNA Ask for price

CSE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721835 1.0 ug DNA Ask for price

CTD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721919 1.0 ug DNA Ask for price

DCE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV722333 1.0 ug DNA Ask for price

DDU Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV722357 1.0 ug DNA Ask for price

RP6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747185 1.0 ug DNA Ask for price

RSS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747629 1.0 ug DNA Ask for price

S11 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747683 1.0 ug DNA Ask for price

S12 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747689 1.0 ug DNA Ask for price

SDU Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV748127 1.0 ug DNA Ask for price

SEA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV748133 1.0 ug DNA Ask for price

RET Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV792597 1.0 ug DNA
EUR 379.2

SFN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV792783 1.0 ug DNA
EUR 379.2

TKT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV807481 1.0 ug DNA
EUR 379.2

TKT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV807487 1.0 ug DNA
EUR 379.2

DCI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV809319 1.0 ug DNA
EUR 379.2

PB1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV811119 1.0 ug DNA
EUR 379.2

GBL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV811197 1.0 ug DNA
EUR 379.2

NMB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV792189 1.0 ug DNA
EUR 379.2

NLP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV811935 1.0 ug DNA
EUR 379.2

DCI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV812301 1.0 ug DNA
EUR 379.2

RIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV812619 1.0 ug DNA
EUR 379.2

HNT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV812739 1.0 ug DNA
EUR 379.2

GAS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV813447 1.0 ug DNA
EUR 379.2

PDR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739871 1.0 ug DNA Ask for price

PIH Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV740315 1.0 ug DNA Ask for price

PRD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV741569 1.0 ug DNA Ask for price

PRS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV741749 1.0 ug DNA Ask for price

JBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730193 1.0 ug DNA Ask for price

JPD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730199 1.0 ug DNA Ask for price

KFM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730349 1.0 ug DNA Ask for price

KMS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730469 1.0 ug DNA Ask for price

KSS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730745 1.0 ug DNA Ask for price

KWE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730751 1.0 ug DNA Ask for price

LCO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730883 1.0 ug DNA Ask for price

GTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV727145 1.0 ug DNA Ask for price

HMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728375 1.0 ug DNA Ask for price

The Intracellular Area of CD40 is a Potent Costimulatory Component in Chimeric Antigen Receptors

The costimulatory domains included into second-generation and third-generation chimeric antigen receptors (CARs) strongly affect CAR-T-cell operate. Right here, we explored second-generation and third-generation CARs harboring the signaling area of the CD40 receptor as a brand new costimulatory aspect as compared with related CARs carrying the 4-1BB area. In CARs of each generations, CD40 was stronger than 4-1BB in triggering the NF-κB signaling pathway.

In human T cells from 2 donors, CD40 was akin to 4-1BB in upregulating costimulatory and activation markers, inducing proinflammatory cytokine secretion and mediating goal cell killing. Apparently, variations within the response sample of T cells from the two donors with respect to CD40 and 4-1BB have been evident. We conclude that in human T cells, the CD40 signaling area is a potent costimulatory aspect in each second-generation and third-generation CARs.

A Systematic Overview of the Function of Chimeric Antigen Receptor T (CAR-T) Cell Remedy within the Therapy of Strong Tumors

Chimeric antigen receptor T (CAR-T) cell remedy makes use of sufferers’ personal T lymphocytes which might be engineered to assault most cancers cells. It’s Meals and Drug Administration (FDA)-approved in numerous hematological malignancies and presently being evaluated in strong cancers in early section research. We did a scientific overview consisting of 15 potential medical trials (n=159) evaluating CAR-T cells in strong cancers. Early section trials confirmed promising response charges in ovarian epithelial most cancers (100%), human epidermal progress issue receptor 2 (HER2)-positive sarcoma (67%), epidermal progress issue receptor (EGFR)-positive biliary tract most cancers (65%), superior gastric/pancreatic most cancers (82%), hepatocellular carcinoma (67%), and colorectal most cancers (70%).

The median general response throughout all malignancies was 62% (vary 17%-100%). Median progression-free survival and general survival weren’t reached in most trials. Cytokine launch syndrome was seen in just one affected person with cholangiocarcinoma who obtained EGFR-specific CAR-T cell remedy. Though survival knowledge continues to be not mature, CAR-T cell remedy in strong malignancies did present encouraging response charges and was well-tolerated.

Variations in lymphoma sufferers between chimeric antigen receptor T-cell remedy trials and the overall inhabitants

Chimeric antigen receptor (CAR)-T cell therapies seem to be promising therapies for non-Hodgkin’s and B-cell lymphoma. Nonetheless, a number of CAR-T therapies accredited by the US Meals and Drug Administration have solely been examined for efficacy in comparatively few single-arm medical trials with small pattern sizes. We sought to look at the variations between sufferers in these trials and the overall inhabitants of sufferers with non-Hodgkin’s and B-cell lymphoma. 5 hundred and twenty-two sufferers from 15 CAR-T trials present in a scientific overview and 417,492 sufferers from the Surveillance, Epidemiology, and Finish Outcomes (SEER) Program database have been in contrast.

CAR-T research individuals seemed to be youthful (46.7% beneath 70 years previous vs. 42.2%), extra male (68.0% vs. 55.7%), and adopted for a shorter time period in comparison with sufferers within the SEER inhabitants (imply [M] 45.6 months, 95% confidence interval [CI] 17.7 to 63.three months follow-up vs. M 57.1 months, 95% CI 57.Zero to 57.three months survival). CAR-T research individuals might differ considerably from the overall inhabitants of sufferers with non-Hodgkin’s and B-cell lymphoma. Effectiveness of CAR-T therapies within the common inhabitants of lymphoma sufferers might differ from effectiveness demonstrated in trials. Newly created CAR-T affected person registries are important to establishing population-level effectiveness of the therapies.

Recombinant Human ITGB1 Protein, His, E.coli-10ug

QP12462-HIS-10ug 10ug
EUR 241.2

Recombinant Human ITGB1 Protein, His, E.coli-20ug

QP12462-HIS-20ug 20ug
EUR 241.2

Recombinant Human ITGB1 Protein, His, E.coli-2ug

QP12462-HIS-2ug 2ug
EUR 186

Recombinant Human ITGB1 Protein, His, E.coli-5ug

QP12462-HIS-5ug 5ug
EUR 186

Recombinant Human ITGB1 Protein, His, E.coli-1mg

QP12462-HIS-EC-1mg 1mg
EUR 3308.4

Human ITGA6 & ITGB1 Protein, His Tag

E40KMPH5766 20ug
EUR 495

ITGB1 protein (His tag)

80R-3617 100 ug
EUR 337
Description: Purified recombinant ITGB1 protein (His tag)

Human Integrin b1 / ITGB1 / CD29, His Tag

E24PHA397 50 μg
EUR 332

Human ITGA8 & ITGB1 Protein, His & Flag Tag

E40KMPH5768 20ug
EUR 495

Recombinant Human CD29/ITGB1 Protein, His Tag

E40KMH184 20ug
EUR 495

GWB-PPST15-100UG - HBG2, 1-147aa Human, His tag, E.coli

GWB-PPST15-100UG 100ug
EUR 330

GWB-PPST15-500UG - HBG2, 1-147aa Human, His tag, E.coli

GWB-PPST15-500UG 500ug
EUR 990

GWB-L628EE-50UG - NRG4, 1-61aa, Human, His tag, E.coli

GWB-L628EE-50UG 50ug
EUR 440

GWB-L628EE-250UG - NRG4, 1-61aa, Human, His tag, E.coli

GWB-L628EE-250UG 250ug
EUR 1320

Rat ITGA8 & ITGB1 Heterodimer Protein, His Tag&Tag Free

IT1-R53W6 1mg
EUR 438.7
Description: Rat ITGA8 & ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R53W6) is expressed from CHO cells. It contains AA Phe 38 - Pro 1034 (ITGA8) & Gln 21 - Asp 729 (ITGB1) (Accession # F7F1E3 (ITGA8) & P49134 (ITGB1)).

Recombinant Human ITGB1/Integrin beta-1/CD29 Protein, His Tag

E40KMP1531 20ug
EUR 495

GWB-ATG116-100UG - BGN, 38-368aa, Human, His tag, E.coli, Recombinant Protein

GWB-ATG116-100UG 100ug
EUR 330

GWB-ATG116-500UG - BGN, 38-368aa, Human, His tag, E.coli, Recombinant Protein

GWB-ATG116-500UG 500ug
EUR 990

GWB-ATG281-50UG - HBG1, 1-147aa, Human, His tag, E.coli, Recombinant Protein

GWB-ATG281-50UG 50ug
EUR 440

GWB-ATG099-50UG - CDH11, 54-617aa, Human, His tag, E.coli, Recombinant Protein

GWB-ATG099-50UG 50ug
EUR 330

GWB-ATG281-250UG - HBG1, 1-147aa, Human, His tag, E.coli, Recombinant Protein

GWB-ATG281-250UG 250ug
EUR 1320

GWB-ATG099-250UG - CDH11, 54-617aa, Human, His tag, E.coli, Recombinant Protein

GWB-ATG099-250UG 250ug
EUR 990

GWB-ATG221-100UG - TARDBP, 1-414aa, Human, His tag, E.coli, Recombinant Protein

GWB-ATG221-100UG 100ug
EUR 330

GWB-ATG221-500UG - TARDBP, 1-414aa, Human, His tag, E.coli, Recombinant Protein

GWB-ATG221-500UG 500ug
EUR 990

Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52E1 1mg
EUR 395.9
Description: Human ITGAV&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52E1) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) & Gln 21 - Asp 728 (ITGB1) (Accession # NP_002201.1 (ITGAV) & NP_002202.2 (ITGB1)).

Human Integrin alpha 4 beta 1 (ITGA4&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52W1 100ug
EUR 3424
Description: Human ITGA4&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W1) is expressed from human 293 cells (HEK293). It contains AA Tyr 34 - Thr 977 (ITGA4) & Gln 21 - Asp 728 (ITGB1) (Accession # P13612-1 (ITGA4) & P05556-1 (ITGB1)).

Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52W5 100ug
EUR 3424
Description: Human ITGA5&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W5) is expressed from human 293 cells (HEK293). It contains AA Phe 42 - Tyr 995 (ITGA5) & Gln 21 - Asp 728 (ITGB1) (Accession # P08648-1 (ITGA5) & P05556-1 (ITGB1)).

Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52W6 100ug
EUR 3424
Description: Human ITGA2&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W6) is expressed from human 293 cells (HEK293). It contains AA Tyr 30 - Thr 1132 (ITGA2) & Gln 21 - Asp 728 (ITGB1) (Accession # P17301-1 (ITGA2) & P05556-1 (ITGB1)).

Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52W7 100ug
EUR 3424
Description: Human ITGA6&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W7) is expressed from human 293 cells (HEK293). It contains AA Phe 24 - Gly 1012 (ITGA6) & Gln 21 - Asp 728 (ITGB1) (Accession # P23229-2 (ITGA6) & P05556-1 (ITGB1)).

Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52W9 100ug
EUR 3424
Description: Human ITGA8&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W9) is expressed from human 293 cells (HEK293). It contains AA Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1) (Accession # P53708-1 (ITGA8) & P05556-1 (ITGB1)).

Human Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52Wb 100ug
EUR 3424
Description: Human ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52Wb) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Pro 1141 (ITGA1) & Gln 21 - Asp 728 (ITGB1) (Accession # P56199-1 (ITGA1) & P05556-1 (ITGB1)).

Human Integrin alpha 11 beta 1 (ITGA11&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52W3 100ug
EUR 3424
Description: Human ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W3) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Pro 1141 (ITGA11) & Gln 21-Asp 728 (ITGB1) (Accession # Q9UKX5-1 (L524R) (ITGA11) & P05556-1 (ITGB1)).

Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52Wa 100ug
EUR 3424
Description: Human ITGA10&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52Wa) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Ser 1122 (ITGA10) & Gln 21 - Asp 728 (ITGB1) (Accession # O75578-1 (ITGA10) & P05556-1 (ITGB1)).

Human/Mouse alpha 1 beta 1 (ITGA1&ITGB1) Protein, His Tag&Tag Free (MALS verified)

IN1-H52W9 1mg
EUR 438.7
Description: Human/Mouse ITGA1&ITGB1 Protein, His Tag&Tag Free (IN1-H52W9) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Pro1141 & Gln 21 - Asp 728 (Accession # P56199-1 & P09055-1).

Recombinant Mouse ITGB1/ Integrin beta-1/ CD29 Protein, His, E.coli-100ug

QP6241-ec-100ug 100ug
EUR 685.2

Recombinant Mouse ITGB1/ Integrin beta-1/ CD29 Protein, His, E.coli-200ug

QP6241-ec-200ug 200ug
EUR 1077.6

Recombinant Mouse ITGB1/ Integrin beta-1/ CD29 Protein, His, E.coli-500ug

QP6241-ec-500ug 500ug
EUR 1816.8

Recombinant Mouse ITGB1/ Integrin beta-1/ CD29 Protein, His, E.coli-10ug

QP6241-ec-10ug 10ug
EUR 326.4

Recombinant Mouse ITGB1/ Integrin beta-1/ CD29 Protein, His, E.coli-50ug

QP6241-ec-50ug 50ug
EUR 434.4

Recombinant Mouse ITGB1/ Integrin beta-1/ CD29 Protein, His, E.coli-1mg

QP6241-ec-1mg 1mg
EUR 2763.6

Human Integrin isoform alpha-7X2B beta 1 (ITGA7X2B&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-H52W8 100ug
EUR 3424
Description: Human ITGA7X2B&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W8) is expressed from human 293 cells (HEK293). It contains AA Phe 34 - Trp 1038 (ITGA7X2B) & Gln 21 - Asp 728 (ITGB1) (Accession # Q13683-7 (ITGA7X2B) & P05556-1 (ITGB1)).

Human Integrin b1 / ITGB1 / CD29, Fc Tag

E24PHA396 50 μg
EUR 332

Recombinant Rat ITGB1/ Integrin beta-1/ CD29 Protein, His-SUMO, E.coli-100ug

QP6242-ec-100ug 100ug
EUR 685.2

Recombinant Rat ITGB1/ Integrin beta-1/ CD29 Protein, His-SUMO, E.coli-200ug

QP6242-ec-200ug 200ug
EUR 1077.6

Recombinant Rat ITGB1/ Integrin beta-1/ CD29 Protein, His-SUMO, E.coli-500ug

QP6242-ec-500ug 500ug
EUR 1816.8

Recombinant Rat ITGB1/ Integrin beta-1/ CD29 Protein, His-SUMO, E.coli-10ug

QP6242-ec-10ug 10ug
EUR 326.4

Recombinant Rat ITGB1/ Integrin beta-1/ CD29 Protein, His-SUMO, E.coli-50ug

QP6242-ec-50ug 50ug
EUR 434.4

Human Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified)

IT1-H52Wc 100ug
EUR 3424
Description: Human ITGA3&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52Wc) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Glu 991 (ITGA3) & Gln 21 - Asp 728 (ITGB1) (Accession # P26006-2 (ITGA3) & P05556-1 (ITGB1)).

Human ITGA1&ITGB1 Heterodimer Protein (Phe 29-Pro 1141 (ITGA1)&Gln 21-Asp 728 (ITGB1))

VAng-1839Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGA1&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P56199-1 (ITGA1)&P05556-1 (ITGB1))

Human ITGA1&ITGB1 Heterodimer Protein (Phe 29-Pro 1141 (ITGA1)&Gln 21-Asp 728 (ITGB1))

VAng-1839Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGA1&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P56199-1 (ITGA1)&P05556-1 (ITGB1))

Human ITGA8&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1847Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGA8&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P53708-1 (ITGA8)&P05556-1 (ITGB1))

Human ITGA8&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1847Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGA8&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P53708-1 (ITGA8)&P05556-1 (ITGB1))

Human ITGA9&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1848Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGA9&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q13797-1 (ITGA9)&P05556-1 (ITGB1))

Human ITGA9&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1848Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGA9&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q13797-1 (ITGA9)&P05556-1 (ITGB1))

Human ITGA4&ITGB1 Heterodimer Protein (Tyr 34-Thr 977 (ITGA4)&Gln 21-Asp 728 (ITGB1))

VAng-1842Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGA4&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P13612-1 (ITGA4)&P05556-1 (ITGB1))

Human ITGA4&ITGB1 Heterodimer Protein (Tyr 34-Thr 977 (ITGA4)&Gln 21-Asp 728 (ITGB1))

VAng-1842Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGA4&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P13612-1 (ITGA4)&P05556-1 (ITGB1))

Human ITGA5&ITGB1 Heterodimer Protein (Phe 42-Tyr 995 (ITGA5)&Gln 21-Asp 728 (ITGB1))

VAng-1844Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGA5&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P08648-1 (ITGA5)&P05556-1 (ITGB1))

Human ITGA5&ITGB1 Heterodimer Protein (Phe 42-Tyr 995 (ITGA5)&Gln 21-Asp 728 (ITGB1))

VAng-1844Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGA5&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P08648-1 (ITGA5)&P05556-1 (ITGB1))

Human ITGAV&ITGB1 Heterodimer Protein (Phe 31-Val 992 (ITGAV)&Gln 21-Asp 728 (ITGB1))

VAng-1852Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGAV&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: NP_002201.1 (ITGAV)&P05556-1 (ITGB1))

Human ITGAV&ITGB1 Heterodimer Protein (Phe 31-Val 992 (ITGAV)&Gln 21-Asp 728 (ITGB1))

VAng-1852Lsx-200g 200 µg
EUR 9562.8
Description: Human ITGAV&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: NP_002201.1 (ITGAV)&P05556-1 (ITGB1))

Recombinant Rat ITGB1/ Integrin beta-1/ CD29 Protein, His-SUMO, E.coli-1mg

QP6242-ec-1mg 1mg
EUR 2763.6

Human ITGA10&ITGB1 Heterodimer Protein (Phe 23-Ser 1122 (ITGA10)&Gln 21-Asp 728 (ITGB1))

VAng-1840Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGA10&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: O75578-1 (ITGA10)&P05556-1 (ITGB1))

Human ITGA10&ITGB1 Heterodimer Protein (Phe 23-Ser 1122 (ITGA10)&Gln 21-Asp 728 (ITGB1))

VAng-1840Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGA10&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: O75578-1 (ITGA10)&P05556-1 (ITGB1))

Human ITGA11&ITGB1 Heterodimer Protein (Phe 23-Ser 1122 (ITGA10)&Gln 21-Asp 728 (ITGB1))

VAng-1841Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGA11&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q9UKX5-1 (L524R) (ITGA11)&P05556-1 (ITGB1))

Human ITGA11&ITGB1 Heterodimer Protein (Phe 23-Ser 1122 (ITGA10)&Gln 21-Asp 728 (ITGB1))

VAng-1841Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGA11&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q9UKX5-1 (L524R) (ITGA11)&P05556-1 (ITGB1))

Human ITGA7X2B&ITGB1 Heterodimer Protein (Phe 34-Trp 1038 (ITGA7X2B)&Gln 21-Asp 728 (ITGB1))

VAng-1846Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGA7X2B&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q13683-7 (ITGA7X2B)&P05556-1 (ITGB1))

Human ITGA7X2B&ITGB1 Heterodimer Protein (Phe 34-Trp 1038 (ITGA7X2B)&Gln 21-Asp 728 (ITGB1))

VAng-1846Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGA7X2B&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: Q13683-7 (ITGA7X2B)&P05556-1 (ITGB1))

Recombinant Human ITGB1BP3 Protein, His, E.coli-100ug

QP12463-100ug 100ug
EUR 1513.2

Recombinant Human ITGB1BP3 Protein, His, E.coli-10ug

QP12463-10ug 10ug
EUR 241.2

Human ITGA6&ITGB1 Heterodimer Protein (Phe 24-Gly 1012 (ITGA6) and Gln 21-Asp 728 (ITGB1))

VAng-1845Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGA6&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P23229-2 (ITGA6)&P05556-1 (ITGB1))

Human ITGA6&ITGB1 Heterodimer Protein (Phe 24-Gly 1012 (ITGA6) and Gln 21-Asp 728 (ITGB1))

VAng-1845Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGA6&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P23229-2 (ITGA6)&P05556-1 (ITGB1))

Recombinant Human ITGB1BP3 Protein, His, E.coli-2ug

QP12463-2ug 2ug
EUR 186

Biotinylated Human ITGA8&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1624Lsx-200g 200 µg
EUR 4612.8
Description: Biotinylated Human ITGA8&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P53708-1 (ITGA8)&P05556-1 (ITGB1))

Biotinylated Human ITGA8&ITGB1 Heterodimer Protein (Phe 39-Leu 1012 (ITGA8)&Gln 21-Asp 728 (ITGB1))

VAng-1624Lsx-25g 25 µg
EUR 1215.6
Description: Biotinylated Human ITGA8&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P53708-1 (ITGA8)&P05556-1 (ITGB1))

Biotinylated Human ITGA4&ITGB1 Heterodimer Protein (Tyr 34-Thr 977 (ITGA4)&Gln 21-Asp 728 (ITGB1))

VAng-1621Lsx-200g 200 µg
EUR 4612.8
Description: Biotinylated Human ITGA4&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P13612-1 (ITGA4)&P05556-1 (ITGB1))

Biotinylated Human ITGA4&ITGB1 Heterodimer Protein (Tyr 34-Thr 977 (ITGA4)&Gln 21-Asp 728 (ITGB1))

VAng-1621Lsx-25g 25 µg
EUR 1215.6
Description: Biotinylated Human ITGA4&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P13612-1 (ITGA4)&P05556-1 (ITGB1))

Biotinylated Human ITGA5&ITGB1 Heterodimer Protein (Phe 42-Tyr 995 (ITGA5)&Gln 21-Asp 728 (ITGB1))

VAng-1623Lsx-200g 200 µg
EUR 4612.8
Description: Biotinylated Human ITGA5&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P08648-1 (ITGA5)&P05556-1 (ITGB1))

Biotinylated Human ITGA5&ITGB1 Heterodimer Protein (Phe 42-Tyr 995 (ITGA5)&Gln 21-Asp 728 (ITGB1))

VAng-1623Lsx-25g 25 µg
EUR 1215.6
Description: Biotinylated Human ITGA5&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P08648-1 (ITGA5)&P05556-1 (ITGB1))

Biotinylated Human ITGAV&ITGB1 Heterodimer Protein (Phe 31-Val 992 (ITGAV)&Gln 21-Asp 728 (ITGB1))

VAng-1625Lsx-200g 200 µg
EUR 4612.8
Description: Biotinylated Human ITGAV&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: NP_002201.1 (ITGAV)&P05556-1 (ITGB1))

Biotinylated Human ITGAV&ITGB1 Heterodimer Protein (Phe 31-Val 992 (ITGAV)&Gln 21-Asp 728 (ITGB1))

VAng-1625Lsx-25g 25 µg
EUR 1215.6
Description: Biotinylated Human ITGAV&ITGB1 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: NP_002201.1 (ITGAV)&P05556-1 (ITGB1))

Recombinant Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, Avi His Tag

E40KMP2046 20ug
EUR 495

Rat Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-R52E1 100ug
EUR 3028.1
Description: Rat ITGAV&ITGB1 Heterodimer, His Tag&Tag Free (IT1-R52E1) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Pro 988 & Gln 21 - Asp 729 (Accession # NP_001385621.1 & P49134-1).

Rat Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-R52W7 100ug
EUR 3113.7
Description: Rat ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R52W7) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Pro 1142 (ITGA1) & Gln 21 - Asp 729 (ITGB1) (Accession # P18614-1 (ITGA1) & P49134-1 (ITGB1)).

Rat Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-R52W9 100ug
EUR 3424
Description: Rat ITGA2&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R52W9) is expressed from human 293 cells (HEK293). It contains AA Tyr 27 - Gly 1130 (ITGA2) & Gln 21 - Asp 729 (ITGB1) (Accession # A0A0G2K470-1 (ITGA2) & P49134-1 (ITGB1)).

Rat Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-R53W4 1mg
EUR 438.7
Description: Rat ITGA5&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R53W4) is expressed from CHO cells. It contains AA Pro 61 - Trp 1049 (ITGA5) & Gln 21 - Asp 729 (ITGB1) (Accession # A0A0G2K1E2 (ITGA5) & P49134-1 (ITGB1)).

Rat Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-R53W5 100ug
EUR 3113.7
Description: Rat ITGAV&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R53W5) is expressed from CHO cells. It contains AA Phe 31 - Pro 988 & Gln 21 - Asp 729 (Accession # NP_001385621.1 & P49134-1).

Rat Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-R53W3 1mg
EUR 438.7
Description: Rat ITGA10&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R53W3) is expressed from CHO cells. It contains AA Phe 23 - Ser 1162 (ITGA10) & Gln 21 - Asp 729 (ITGB1) (Accession # D3ZW82-1 (ITGA10) & P49134-1 (ITGB1)).

Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-M52W6 100ug
EUR 3424
Description: Mouse ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-M52W6) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Pro 1141 (ITGA1) & Gln 21 - Asp 728 (ITGB1) (Accession # Q3V3R4-1 (ITGA1) & P09055-1 (ITGB1)).

Recombinant (E.coli) Human CD40 (aa: 21-193, His Tag, >95% Pure)

HCD4015-N-10 10 ug
EUR 343.2

Canine Integrin alpha 11 beta 1 (ITGA11&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-C52W9 100ug
EUR 3113.7
Description: Canine ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-C52W9) is expressed from human 293 cells (HEK293). It contains AA Asp 21 - Pro 1142 (ITGA11) & Asp 23 - Asp 728 (ITGB1) (Accession # A0A8I3S131-1 (ITGA11) & A0A8C0PYR6-1 (ITGB1)).

Mouse Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-M52W4 100ug
EUR 3424
Description: Mouse ITGA10&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-M52W4) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Thr 1118 (ITGA10) & Gln 21 - Asp 728 (ITGB1) (Accession # E9PXZ3-1 (ITGA10) & P09055-1 (ITGB1)).

Mouse Integrin alpha 11 beta 1 (ITGA11&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-M52W5 100ug
EUR 3424
Description: Mouse ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-M52W5) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Pro 1141 (ITGA11) & Gln 21 - Asp 728 (ITGB1) (Accession # P61622-1 (ITGA11) & P09055-1 (ITGB1)).

Cynomolgus Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-C52W4 1mg
EUR 438.7
Description: Cynomolgus Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, His Tag&Tag Free (IT1-C52W4) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Pro 993 & Gln 161 - Asp 868 (Accession # A0A2K5WCD3-1 & A0A7N9D0D7).

Cynomolgus Integrin alpha 11 beta 1 (ITGA1&ITGB1) Heterodimer Protein, His Tag&Tag Free

IT1-C53W3 1mg
EUR 438.7
Description: Cynomolgus ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-C53W3) is expressed from CHO cells. It contains AA Phe 23 - Pro 1131 & Gln 21 – Asp 728 (Accession # A0A2K5U8X4-1 & XP_005564990.1).

Human Integrin b7 / ITGB7, His Tag

E24PHA168 50 μg
EUR 225

Recombinant Human ITGB1 Protein, His, Insect-1mg

QP12462-HIS-INSECT-1mg 1mg
EUR 6301.2

Rat Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified)

IT1-R53Wb 100ug
EUR 3113.7
Description: Rat ITGA3 & ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R53Wb) is expressed from CHO cells. It contains AA Phe 33 - Glu 992 & Gln 21 - Asp 729 (Accession # I4DUB5 & P49134).

Human Integrin b2 / ITGB2 / CD18, His Tag

E24PHA399 50 μg
EUR 332

Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified)

IT1-M52W3 100ug
EUR 3424
Description: Mouse ITGA2&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-M52W3) is expressed from human 293 cells (HEK293). It contains AA Tyr 27 - Thr 1129 (ITGA2) & Gln 21 - Asp 728 (ITGB1) (Accession # Q62469-1 (ITGA2) & P09055-1 (ITGB1)).

Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, Tag Free&Tag Free

IT1-H5213 100ug
EUR 3424
Description: Human ITGAV&ITGB1 Heterodimer Protein, Tag Free&Tag Free (IT1-H5213) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) & Gln 21 - Asp 728 (ITGB1) (Accession # NP_002201.1 (ITGAV) & NP_002202.2 (ITGB1)).

Biotinylated Human Integrin alpha 4 beta 1 (ITGA4&ITGB1) Heterodimer Protein, His,Avitag™&Tag Free

IT1-H82W1 25ug
EUR 1647.8
Description: Biotinylated Human ITGA4&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (IT1-H82W1) is expressed from human 293 cells (HEK293). It contains AA Tyr 34 - Thr 977 (ITGA4) & Gln 21 - Asp 728 (ITGB1) (Accession # P13612-1 (ITGA4) & P05556-1 (ITGB1)).

Biotinylated Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, His,Avitag™&Tag Free

IT1-H82W6 25ug
EUR 1647.8
Description: Biotinylated Human ITGAV&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (IT1-H82W6) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) & Gln 21 - Asp 728 (ITGB1) (Accession # NP_002201.1 (ITGAV) & NP_002202.2 (ITGB1)).

Biotinylated Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, His,Avitag™&Tag Free

IT1-H82Wa 25ug
EUR 1647.8
Description: Biotinylated Human ITGA5&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (IT1-H82Wa) is expressed from human 293 cells (HEK293). It contains AA Phe 42 - Tyr 995 (ITGA5) & Gln 21 - Asp 728 (ITGB1) (Accession # P08648-1 (ITGA5) & P05556-1 (ITGB1)).

Biotinylated Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein, His,Avitag™&Tag Free

IT1-H82Wb 25ug
EUR 1647.8
Description: Biotinylated Human ITGA8&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (IT1-H82Wb) is expressed from human 293 cells (HEK293). It contains AA Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1) (Accession # P53708-1 (ITGA8) & P05556-1 (ITGB1)).

Human ITGAIIb&ITGB3 Heterodimer Protein (Tyr 30-Thr 1132 (ITGA2)&Gln 21-Asp 728 (ITGB1))

VAng-1851Lsx-100g 100 µg
EUR 1413.6
Description: Human ITGAIIb&ITGB3 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P17301-1 (ITGA2)&P05556-1 (ITGB1))

Human ITGAIIb&ITGB3 Heterodimer Protein (Tyr 30-Thr 1132 (ITGA2)&Gln 21-Asp 728 (ITGB1))

VAng-1851Lsx-1mg 1 mg
EUR 9562.8
Description: Human ITGAIIb&ITGB3 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P17301-1 (ITGA2)&P05556-1 (ITGB1))

Human ITGAX & ITGB2 Protein, His & Flag Tag

E40KMPH5769 20ug
EUR 495

Human ITGAV & ITGB6 Protein, His & Flag Tag

E40KMPH5778 20ug
EUR 495

Recombinant Human CD61/ITGB3 Protein, His Tag

E40KMH223 20ug
EUR 495

Recombinant Human CD104/ITGB4 Protein, His Tag

E40KMH278 20ug
EUR 495

ITGB1 Protein Vector (Human) (pPB-C-His)

PV021853 500 ng
EUR 394.8

ITGB1 Protein Vector (Human) (pPB-N-His)

PV021854 500 ng
EUR 394.8

ITGB1 Protein Vector (Human) (pPM-C-His)

PV021856 500 ng
EUR 394.8

Biotinylated Human Integrin isoform alpha-7X2B beta 1 (ITGA7X2B&ITGB1) Heterodimer Protein, Tag Free&His,Avitag™

IT1-H82W5 25ug
EUR 1647.8
Description: Biotinylated Human ITGA7X2B&ITGB1 Heterodimer Protein, Tag Free&His,Avitag (IT1-H82W5) is expressed from human 293 cells (HEK293). It contains AA Phe 34 - Trp 1038 (ITGA7X2B) & Gln 21 - Asp 728 (ITGB1) (Accession # Q13683-7 (ITGA7X2B) & P05556-1 (ITGB1)).

Cynomolgus Integrin isoform alpha-7X1B beta 1 (ITGA7X1B&ITGB1) Heterodimer Protein, Tag Free&His Tag (MALS verified)

IT1-C52W3 100ug
EUR 3424
Description: Cynomolgus ITGA7X1B&ITGB1 Heterodimer Protein, Tag Free&His Tag (IT1-C52W3) is expressed from human 293 cells (HEK293). It contains AA Phe 34 - Pro 1081 (ITGA7X1B) & Gln 21 - Asp 728 (ITGB1) (Accession # XP_005571182.1 (ITGA7X1B) & XP_015311227.1 (ITGB1)).

ITGB1 ELISA KIT|Human

EF006242 96 Tests
EUR 826.8

Human ITGB1 ELISA Kit

ELA-E2224h 96 Tests
EUR 988.8

Human ITGA5 & ITGB1 Protein

E40KMPH5767 20ug
EUR 495

Human ITGAV&ITGB1 Protein

E40KMPH6073 20ug
EUR 495

Human ITGB1 shRNA Plasmid

20-abx952477
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Recombinant Human MOG Protein (E.coli, His Tag)

PKSH032768-10ug 10ug
EUR 86
Description: Human

Recombinant Human MOG Protein (E.coli, His Tag)

PKSH032768-50ug 50ug
EUR 250
Description: Human

Recombinant Human RPE Protein (E.coli, His Tag)

PKSH033347-10ug 10ug
EUR 275
Description: Human

Recombinant Human RPE Protein (E.coli, His Tag)

PKSH033347-50ug 50ug
EUR 525
Description: Human

Recombinant Human CDK2 Protein (E.coli, His Tag)

PDEH100009-100ug 100ug
EUR 118
Description: Human

Recombinant Human CDK2 Protein (E.coli, His Tag)

PDEH100009-20ug 20ug
EUR 68
Description: Human

Recombinant Human RGMA Protein (E.coli, His Tag)

PKSH033343-10ug 10ug
EUR 263
Description: Human

Recombinant Human RGMA Protein (E.coli, His Tag)

PKSH033343-50ug 50ug
EUR 447
Description: Human

Recombinant Human GMPR Protein (E.coli, His Tag)

PKSH030542-100ug 100ug
EUR 855
Description: Human

Recombinant Human IDH1 Protein (E.coli, His Tag)

PKSH030920-1mg 1mg
EUR 6600
Description: Human

Recombinant Human IDH1 Protein (E.coli, His Tag)

PKSH030920-50ug 50ug
EUR 1012
Description: Human

Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein, His Tag&Tag Free

IT2-H52W3 100ug
EUR 3424
Description: Human ITGAX&ITGB2 Heterodimer Protein, His Tag&Tag Free (IT2-H52W3) is expressed from human 293 cells (HEK293). It contains AA Phe 20 -Pro 1107 (ITGAX) & Gln 23 - Asn 700 (ITGB2) (Accession # P20702-1 (ITGAX) & P05107-1 (ITGB2)).

Human Integrin alpha M beta 2 (ITGAM&ITGB2) Heterodimer Protein, His Tag&Tag Free

IT2-H52W4 100ug
EUR 3424
Description: Human ITGAM&ITGB2 Heterodimer Protein, His Tag&Tag Free (IT2-H52W4) is expressed from human 293 cells (HEK293). It contains AA Phe 17 - Asn 1105 (ITGAM) & Gln 23 - Asn 700 (ITGB2) (Accession # P11215-2 (ITGAM) & P05107-1 (ITGB2)).

Human Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein, His Tag&Tag Free

IT2-H53W3 100ug
EUR 3424
Description: Human ITGAL&ITGB2 Heterodimer Protein, His Tag&Tag Free (IT2-H53W3) is expressed from CHO cells. It contains AA Tyr 26 - Met 1089 (ITGAL) & Gln 23 - Asn 700 (ITGB2) (Accession # P20701-1 (ITGAL) & P05107-1 (ITGB2)).

Human Integrin alpha D beta 2 (ITGAD&ITGB2) Heterodimer Protein, His Tag&Tag Free

IT2-H53W6 100ug
EUR 3424
Description: Human ITGAD&ITGB2 Heterodimer Protein, His Tag&Tag Free (IT2-H53W6) is expressed from CHO cells. It contains AA Phe 18 - Asn 1099 (ITGAD) & Gln 23 - Asn 700 (ITGB2) (Accession # Q13349-1 (ITGAD) & P05107-1 (ITGB2)).

Human Integrin alpha V beta 5 (ITGAV&ITGB5) Heterodimer Protein, His Tag&Tag Free

IT5-H52W5 100ug
EUR 3424
Description: Human ITGAV&ITGB5 Heterodimer Protein, His Tag&Tag Free (IT5-H52W5) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) & Gly 24 - Asn 719 (ITGB5) (Accession # NP_002201.1 (ITGAV) & NP_002204.2 (ITGB5)).

Human Integrin alpha E beta 7 (ITGAE&ITGB7) Heterodimer Protein, His Tag&Tag Free

IT7-H52W7 50ug
EUR 3327.7
Description: Human ITGAE&ITGB7 Heterodimer Protein, His Tag&Tag Free (IT7-H52W7) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Ser 1124 (ITGAE) & Glu 20 - His 723 (ITGB7) (Accession # P38570-1 (ITGAE) & P26010-1 (ITGB7)).

Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein, His Tag&Tag Free

IT8-H52W4 100ug
EUR 3424
Description: Human ITGAV&ITGB8 Heterodimer Protein, His Tag&Tag Free (IT8-H52W4) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) & Glu 43 - Arg 684 (ITGB8) (Accession # NP_002201.1 (ITGAV) & NP_002205.1 (ITGB8)).

Recombinant Human STAT6 Protein (E.coli, His Tag)

PKSH033528-10ug 10ug
EUR 178
Description: Human

Recombinant Human STAT6 Protein (E.coli, His Tag)

PKSH033528-50ug 50ug
EUR 523
Description: Human

Human Integrin alpha 2b beta 3 (ITGAIIb&ITGB3) Heterodimer Protein, His Tag&Tag Free

IT3-H52W8 100ug
EUR 3424
Description: Human ITGAIIb&ITGB3 Heterodimer Protein, His Tag&Tag Free (IT3-H52W8) is expressed from human 293 cells (HEK293). It contains AA Leu 32 - Arg 993 (ITGAIIb) & Gly 27 - Asp 718 (ITGB3) (Accession # P08514-1 (ITGAIIb) & P05106-1 (ITGB3)).

ITGB3BP protein (His tag)

80R-2763 20 ug
EUR 329
Description: Purified recombinant ITGB3BP protein (His tag)

Recombinant Human Integrin ITGAV & ITGB3 Protein, Avi His Tag

E40KMP2033 20ug
EUR 495

Recombinant Human Integrin ITGAV & ITGB5 Protein, Avi His Tag

E40KMP2035 20ug
EUR 495

Recombinant Human S100A6 Protein (E.coli, His Tag)

PKSH033391-10ug 10ug
EUR 209
Description: Human

Recombinant Human S100A6 Protein (E.coli, His Tag)

PKSH033391-50ug 50ug
EUR 328
Description: Human

ITGB1 Recombinant Protein (Human)

RP016390 100 ug Ask for price

ITGB1BP3 protein (His tag)

80R-2414 20 ug
EUR 329
Description: Purified recombinant ITGB1BP3 protein (His tag)

Recombinant Human CDK2AP2 Protein (E.coli, His Tag)

PKSH030818-100ug 100ug
EUR 855
Description: Human

Recombinant (E.coli) Sudan Ebola virus VP40 (Uganda,1-326aa, his-MBP tag at NT, >95%)

SVP408-R-10 10 ug
EUR 416.4

Recombinant (E.coli) Sudan Ebola virus VP40 (Uganda,1-326aa, his-MBP tag at NT, >95%)

SVP408-R-100 100 ug
EUR 2617.2

Recombinant (E.coli) Sudan Ebola virus VP40 (Uganda,31-326aa, His-tag, >95%)

SVP407-R-10 10 ug
EUR 416.4

Recombinant (E.coli) Sudan Ebola virus VP40 (Uganda,31-326aa, His-tag, >95%)

SVP407-R-100 100 ug
EUR 2617.2

Recombinant (E.coli) Rat CD40 (aa: 21-193, His Tag, >95% Pure)

RCD4015-N-10 10 ug
EUR 255.6

Recombinant (E.Coli, His-tag) Human Syndecan-4, His-tag

RP-993 10 ug
EUR 270

Recombinant (E.Coli) HIV-1 p24 gag (155-321aa, his-tag at the NT, >95%)

RP-583-8 20 ug
EUR 343.2

Human Coronavirus (OC43) Nucleocapsid Protein, His tag, E.coli

E2S209917P 100ul
EUR 595
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Human Coronavirus (HKU1) Nucleocapsid Protein, His tag, E.coli

E2S209918P 100ul
EUR 595
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Recombinant Human ITGB2 Protein-His tag

CTP-197 100ug Ask for price
Description: A 75.9 kDa recombinant human ITGB2 protein with a C-Terminal His-tag expressed in the Baculovirus.

ITGB1 ORF Vector (Human) (pORF)

ORF005464 1.0 ug DNA
EUR 114

Human ITGB1 knockout cell line

ABC-KH7529 1 vial Ask for price
Description: Human ITGB1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human ITGB1 knockdown cell line

ABC-KD7529 1 vial Ask for price
Description: Human ITGB1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human ITGB1 Protein Lysate 20ug

IHUITGB1PLLY20UG each
EUR 213
Description: Human ITGB1 Protein Lysate 20ug

ITGB1 ELISA Kit (Human) (OKCD02658)

OKCD02658 96 Wells
EUR 950.4
Description: Description of target: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGA4:ITGB1 and ITGA5:ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.1;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.32 ng/mL

ITGB1 ELISA Kit (Human) (OKAN04766)

OKAN04766 96 Wells
EUR 950.4
Description: Description of target: Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.35 ng/mL

ITGB1 ELISA Kit (Human) (OKEH07016)

OKEH07016 96 Wells
EUR 794.4
Description: Description of target: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGA4:ITGB1 and ITGA5:ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.1;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 10 pg/mL

Itgb1/ Rat Itgb1 ELISA Kit

ELI-07117r 96 Tests
EUR 1063.2

Recombinant (E.Coli, His-tag) Human CD29

RP-915 2 ug
EUR 416.4

ITGB1

ant-715 5µg
EUR 60
Description: Mouse Anti Human Integrin Beta 1

ITGB1

CSB-CL011880HU 10 μg plasmid + 200μl Glycerol Ask for price

ITGB1

pro-1817 5µg
EUR 60
Description: Recombinant Human Integrin Beta 1

Recombinant (E.Coli, His-tag) Human HTRA2

RP-413 10 ug
EUR 270

Recombinant (E.Coli, His-tag) Human STAT1

RP-722 10 ug
EUR 343.2

Recombinant (E.Coli, His-tag) Human S100b

RP-774 10 ug
EUR 343.2

Human IL-21, His Tag

E24PHA161 50 μg
EUR 262

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